USP5‐dependent HDAC1 promotes cisplatin resistance and the malignant progression of non–small cell lung cancer by regulating RILP acetylation levels

USP5‐dependent HDAC1 promotes cisplatin resistance and the malignant progression of non–small cell lung cancer by regulating RILP acetylation levels

Abstract Background Non‐small cell lung cancer (NSCLC) is a leading cause of cancer‐related deaths worldwide, with cisplatin (DDP) resistance being a significant challenge in its treatment. Histone deacetylase 1 (HDAC1) has been implicated in the regulation of NSCLC progression; however, its role in...

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Bibliographic Details
Main Authors: Rongguo Lu, Yulin Jin, Mingfeng Zheng
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Thoracic Cancer
Subjects:
DDP
HDAC1
NSCLC
RILP
USP5
Online Access:https://doi.org/10.1111/1759-7714.15478
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