Association of neutrophil-to-lymphocyte ratio and monocyte-tolymphocyte ratio with all-cause mortality in patients with ischemia and non-obstructive coronary arteries
Ischemia with non-obstructive coronary arteries (INOCA) is a frequent coronary syndrome with important impact on morbimortality. Systemic inflammation, a key pathophysiological mechanism in its development, is reflected in diverse bio-markers, such as the neutrophil-to-lymphocyte ratio (NLR), monocy...
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| Format: | Article |
| Language: | English |
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Sciendo
2025-01-01
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| Series: | Romanian Journal of Laboratory Medicine |
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| Online Access: | https://doi.org/10.2478/rrlm-2025-0004 |
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| author | Mihai Emilian Dumitru Delcea Caterina Buzea Adrian Cătălin Dan Gheorghe-Andrei |
| author_facet | Mihai Emilian Dumitru Delcea Caterina Buzea Adrian Cătălin Dan Gheorghe-Andrei |
| author_sort | Mihai Emilian Dumitru |
| collection | DOAJ |
| description | Ischemia with non-obstructive coronary arteries (INOCA) is a frequent coronary syndrome with important impact on morbimortality. Systemic inflammation, a key pathophysiological mechanism in its development, is reflected in diverse bio-markers, such as the neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR) and platelet-to-lymphocyte ratio (PLR). In this retrospective observational study, we aimed to assess the value of NLR, MLR and PLR as predictors of all-cause long-term mortality in INOCA patients. |
| format | Article |
| id | doaj-art-ba2595f67b4b4f46a510ff5c9f1e2f0f |
| institution | Kabale University |
| issn | 2284-5623 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Romanian Journal of Laboratory Medicine |
| spelling | doaj-art-ba2595f67b4b4f46a510ff5c9f1e2f0f2025-02-10T13:26:16ZengSciendoRomanian Journal of Laboratory Medicine2284-56232025-01-01331212810.2478/rrlm-2025-0004Association of neutrophil-to-lymphocyte ratio and monocyte-tolymphocyte ratio with all-cause mortality in patients with ischemia and non-obstructive coronary arteriesMihai Emilian Dumitru0Delcea Caterina1Buzea Adrian Cătălin2Dan Gheorghe-Andrei3Department of Cardiology, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Cardiology, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Cardiology, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Cardiology, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaIschemia with non-obstructive coronary arteries (INOCA) is a frequent coronary syndrome with important impact on morbimortality. Systemic inflammation, a key pathophysiological mechanism in its development, is reflected in diverse bio-markers, such as the neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR) and platelet-to-lymphocyte ratio (PLR). In this retrospective observational study, we aimed to assess the value of NLR, MLR and PLR as predictors of all-cause long-term mortality in INOCA patients.https://doi.org/10.2478/rrlm-2025-0004inocaischemia with non-obstructive coronary artery diseasemonocyte-to-lymphocyte ratio (mlr)neutrophil-tolymphocyte ratio (nlr)platelet-to-lymphocyte ratio (plr) |
| spellingShingle | Mihai Emilian Dumitru Delcea Caterina Buzea Adrian Cătălin Dan Gheorghe-Andrei Association of neutrophil-to-lymphocyte ratio and monocyte-tolymphocyte ratio with all-cause mortality in patients with ischemia and non-obstructive coronary arteries Romanian Journal of Laboratory Medicine inoca ischemia with non-obstructive coronary artery disease monocyte-to-lymphocyte ratio (mlr) neutrophil-tolymphocyte ratio (nlr) platelet-to-lymphocyte ratio (plr) |
| title | Association of neutrophil-to-lymphocyte ratio and monocyte-tolymphocyte ratio with all-cause mortality in patients with ischemia and non-obstructive coronary arteries |
| title_full | Association of neutrophil-to-lymphocyte ratio and monocyte-tolymphocyte ratio with all-cause mortality in patients with ischemia and non-obstructive coronary arteries |
| title_fullStr | Association of neutrophil-to-lymphocyte ratio and monocyte-tolymphocyte ratio with all-cause mortality in patients with ischemia and non-obstructive coronary arteries |
| title_full_unstemmed | Association of neutrophil-to-lymphocyte ratio and monocyte-tolymphocyte ratio with all-cause mortality in patients with ischemia and non-obstructive coronary arteries |
| title_short | Association of neutrophil-to-lymphocyte ratio and monocyte-tolymphocyte ratio with all-cause mortality in patients with ischemia and non-obstructive coronary arteries |
| title_sort | association of neutrophil to lymphocyte ratio and monocyte tolymphocyte ratio with all cause mortality in patients with ischemia and non obstructive coronary arteries |
| topic | inoca ischemia with non-obstructive coronary artery disease monocyte-to-lymphocyte ratio (mlr) neutrophil-tolymphocyte ratio (nlr) platelet-to-lymphocyte ratio (plr) |
| url | https://doi.org/10.2478/rrlm-2025-0004 |
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