The Current Insecticide Resistance in Main Malaria Vector Anopheles arabiensis in Yemen

Control of malaria vectors in Yemen relies on both indoor residual spraying using carbamate (bendiocarb) and long-lasting pyrethroids-treated nets. This paper reports the results of studies conducted to monitor the insecticide resistance of the main malaria vector, Anopheles arabiensis, to the insec...

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Main Authors: Zalalham Al-Koleeby, Ahmed El Aboudi, Mithaq Assada, Mohamed Al-Hadi, Mohammed Abdalr Ahman, Abdullah Awash, Abdul Samad Ahmed, Hani Mohamedi, Jamil Al Jarbany, Chafika Faraj
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Tropical Medicine
Online Access:http://dx.doi.org/10.1155/2020/5625019
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author Zalalham Al-Koleeby
Ahmed El Aboudi
Mithaq Assada
Mohamed Al-Hadi
Mohammed Abdalr Ahman
Abdullah Awash
Abdul Samad Ahmed
Hani Mohamedi
Jamil Al Jarbany
Chafika Faraj
author_facet Zalalham Al-Koleeby
Ahmed El Aboudi
Mithaq Assada
Mohamed Al-Hadi
Mohammed Abdalr Ahman
Abdullah Awash
Abdul Samad Ahmed
Hani Mohamedi
Jamil Al Jarbany
Chafika Faraj
author_sort Zalalham Al-Koleeby
collection DOAJ
description Control of malaria vectors in Yemen relies on both indoor residual spraying using carbamate (bendiocarb) and long-lasting pyrethroids-treated nets. This paper reports the results of studies conducted to monitor the insecticide resistance of the main malaria vector, Anopheles arabiensis, to the insecticides currently used in the vector control in four different locations. Susceptibility tests were performed following the WHO test procedures. Two pyrethroids (lambda-cyhalothrin 0.05% and deltamethrin 0.05%) and one carbamate (bendiocarb 0.1%) were tested at diagnostic doses (DD). The five-fold DD of lambda-cyhalothrin and deltamethrin (0.25%) were also used to yield information on the intensity of resistance. Besides, tests with synergists were performed to assess the involvement of detoxifying enzyme in the phenotypic resistance of the populations of An. arabiensis to pyrethroids. The results of the performed susceptibility bioassay showed that the vector is susceptible to bendiocarb and resistant to lambda-cyhalothrin and deltamethrin in the four studied areas. The pyrethroids resistance is solely metabolic. This information could help policy-makers to plan insecticide resistance management. Bendiocarb is still an effective insecticide in the form of IRS. Concerning LLINS, it would be interesting to assess their effectiveness, combining a pyrethroid with PBO for the control of the pyrethroid-resistant malaria vector.
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spelling doaj-art-ba1c32d814f840aea99aa617e6b74bd82025-08-20T03:23:22ZengWileyJournal of Tropical Medicine1687-96861687-96942020-01-01202010.1155/2020/56250195625019The Current Insecticide Resistance in Main Malaria Vector Anopheles arabiensis in YemenZalalham Al-Koleeby0Ahmed El Aboudi1Mithaq Assada2Mohamed Al-Hadi3Mohammed Abdalr Ahman4Abdullah Awash5Abdul Samad Ahmed6Hani Mohamedi7Jamil Al Jarbany8Chafika Faraj9Plant and Microbial Biotechnology, Biodiversity and the Environment, Faculty of Science, Agdal University, Rabat, MoroccoPlant and Microbial Biotechnology, Biodiversity and the Environment, Faculty of Science, Agdal University, Rabat, MoroccoNational Malaria Control Program, Ministry of Health and Population, Sana’a, YemenNational Malaria Control Program, Ministry of Health and Population, Sana’a, YemenNational Malaria Control Program, Ministry of Health and Population, Sana’a, YemenNational Malaria Control Program, Ministry of Health and Population, Sana’a, YemenNational Malaria Control Program, Ministry of Health and Population, Sana’a, YemenNational Malaria Control Program, Ministry of Health and Population, Sana’a, YemenNational Malaria Control Program, Ministry of Health and Population, Sana’a, YemenLaboratory of Medical Entomology, National Institute of Hygiene, Rabat, MoroccoControl of malaria vectors in Yemen relies on both indoor residual spraying using carbamate (bendiocarb) and long-lasting pyrethroids-treated nets. This paper reports the results of studies conducted to monitor the insecticide resistance of the main malaria vector, Anopheles arabiensis, to the insecticides currently used in the vector control in four different locations. Susceptibility tests were performed following the WHO test procedures. Two pyrethroids (lambda-cyhalothrin 0.05% and deltamethrin 0.05%) and one carbamate (bendiocarb 0.1%) were tested at diagnostic doses (DD). The five-fold DD of lambda-cyhalothrin and deltamethrin (0.25%) were also used to yield information on the intensity of resistance. Besides, tests with synergists were performed to assess the involvement of detoxifying enzyme in the phenotypic resistance of the populations of An. arabiensis to pyrethroids. The results of the performed susceptibility bioassay showed that the vector is susceptible to bendiocarb and resistant to lambda-cyhalothrin and deltamethrin in the four studied areas. The pyrethroids resistance is solely metabolic. This information could help policy-makers to plan insecticide resistance management. Bendiocarb is still an effective insecticide in the form of IRS. Concerning LLINS, it would be interesting to assess their effectiveness, combining a pyrethroid with PBO for the control of the pyrethroid-resistant malaria vector.http://dx.doi.org/10.1155/2020/5625019
spellingShingle Zalalham Al-Koleeby
Ahmed El Aboudi
Mithaq Assada
Mohamed Al-Hadi
Mohammed Abdalr Ahman
Abdullah Awash
Abdul Samad Ahmed
Hani Mohamedi
Jamil Al Jarbany
Chafika Faraj
The Current Insecticide Resistance in Main Malaria Vector Anopheles arabiensis in Yemen
Journal of Tropical Medicine
title The Current Insecticide Resistance in Main Malaria Vector Anopheles arabiensis in Yemen
title_full The Current Insecticide Resistance in Main Malaria Vector Anopheles arabiensis in Yemen
title_fullStr The Current Insecticide Resistance in Main Malaria Vector Anopheles arabiensis in Yemen
title_full_unstemmed The Current Insecticide Resistance in Main Malaria Vector Anopheles arabiensis in Yemen
title_short The Current Insecticide Resistance in Main Malaria Vector Anopheles arabiensis in Yemen
title_sort current insecticide resistance in main malaria vector anopheles arabiensis in yemen
url http://dx.doi.org/10.1155/2020/5625019
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