Recirculation of digestive enzymes
The aim of review. To present literature data and to generalize accumulated by the author and his employees experimental and clinical material on the mechanisms of enzyme transport to systemic blood flow, process of recretion of enzymes by digestive glands in the lumen of gut and the functional role...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2011-06-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1432 |
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| _version_ | 1823860225947467776 |
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| author | G. F. Korot'ko |
| author_facet | G. F. Korot'ko |
| author_sort | G. F. Korot'ko |
| collection | DOAJ |
| description | The aim of review. To present literature data and to generalize accumulated by the author and his employees experimental and clinical material on the mechanisms of enzyme transport to systemic blood flow, process of recretion of enzymes by digestive glands in the lumen of gut and the functional role of circulating hydrolases.Original positions. Digestive glands exosecrete two pools of hydrolases: postprandially de novo synthesized and recreted from blood circulation, to which they are transported by three mechanisms – endosecretion of glandular cells, resorption of hydrolases from ductal system of the glands and the small bowel. Enzymes, being switched off from circulation by recretion, are involved in gastro-intestinal digestion and carry out a signal role in modulation of secretory, motor and absorptive functions of the gut. Circulation and recretion of enzymes, their reutilization in alimentary process fit into principle of energetic and plastic economization in alimentary functions.Conclusion. The principle of enterohepatic circulation of bile acids in general view is repeated at interorgan recirculation of hydrolases of the digestive glands providing process of digestion, and by enzyme signaling – integration and adaptation of functions of the gut organs by modulating effects. |
| format | Article |
| id | doaj-art-ba12d425c99e4b6d8b3fc7f35a45c18d |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2011-06-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-ba12d425c99e4b6d8b3fc7f35a45c18d2025-02-10T16:14:31ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732011-06-012141421968Recirculation of digestive enzymesG. F. Korot'ko0МУЗ «Городская больница № 2The aim of review. To present literature data and to generalize accumulated by the author and his employees experimental and clinical material on the mechanisms of enzyme transport to systemic blood flow, process of recretion of enzymes by digestive glands in the lumen of gut and the functional role of circulating hydrolases.Original positions. Digestive glands exosecrete two pools of hydrolases: postprandially de novo synthesized and recreted from blood circulation, to which they are transported by three mechanisms – endosecretion of glandular cells, resorption of hydrolases from ductal system of the glands and the small bowel. Enzymes, being switched off from circulation by recretion, are involved in gastro-intestinal digestion and carry out a signal role in modulation of secretory, motor and absorptive functions of the gut. Circulation and recretion of enzymes, their reutilization in alimentary process fit into principle of energetic and plastic economization in alimentary functions.Conclusion. The principle of enterohepatic circulation of bile acids in general view is repeated at interorgan recirculation of hydrolases of the digestive glands providing process of digestion, and by enzyme signaling – integration and adaptation of functions of the gut organs by modulating effects.https://www.gastro-j.ru/jour/article/view/1432enzymes of digestive glandsexosecretionendosecretionrecretionresorptionrecirculation of enzymesphysiological role |
| spellingShingle | G. F. Korot'ko Recirculation of digestive enzymes Российский журнал гастроэнтерологии, гепатологии, колопроктологии enzymes of digestive glands exosecretion endosecretion recretion resorption recirculation of enzymes physiological role |
| title | Recirculation of digestive enzymes |
| title_full | Recirculation of digestive enzymes |
| title_fullStr | Recirculation of digestive enzymes |
| title_full_unstemmed | Recirculation of digestive enzymes |
| title_short | Recirculation of digestive enzymes |
| title_sort | recirculation of digestive enzymes |
| topic | enzymes of digestive glands exosecretion endosecretion recretion resorption recirculation of enzymes physiological role |
| url | https://www.gastro-j.ru/jour/article/view/1432 |
| work_keys_str_mv | AT gfkorotko recirculationofdigestiveenzymes |