Spectrum of Somatic Malignancy in Testicular Germ Cell Tumors—A Histopathological Review of 25 Cases with Clinical Outcome

Spectrum of Somatic Malignancy in Testicular Germ Cell Tumors—A Histopathological Review of 25 Cases with Clinical Outcome

Introduction Germ cell tumors (GCTs) are the commonest testicular malignancy in young males. These tumors are highly chemoresponsive, however become resistant to conventional therapy when a somatic-type malignancy (SM) develops, which happens in ∼3 to 6% of the cases.

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Bibliographic Details
Main Authors: Priyadarsani Subramanian, Amandeep Arora, Mahendra Pal, Gagan Prakash, Priyamvada Maitre, Vedang Murthy, Amit Joshi, Swapnil Rane, Sangeeta Desai, Santosh Menon
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2025-04-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
germ cell tumors
somatic malignancy
embryonic-type neuroectodermal tumors
rhabdomyosarcoma
teratomatous overgrowth
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788307
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Summary:Introduction Germ cell tumors (GCTs) are the commonest testicular malignancy in young males. These tumors are highly chemoresponsive, however become resistant to conventional therapy when a somatic-type malignancy (SM) develops, which happens in ∼3 to 6% of the cases.
ISSN:0971-5851
0975-2129

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