Modular scaffolds with intelligent visual guidance system for in situ bone tissue repair
In clinical practice, the irregular shapes of traumas pose a significant challenge in rapidly manufacturing personalized scaffolds. To address these challenges, inspired by LEGO ^® bricks, this study proposed a novel concept of modular scaffolds and developed an innovative system based on machine vi...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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IOP Publishing
2024-01-01
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| Series: | International Journal of Extreme Manufacturing |
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| Online Access: | https://doi.org/10.1088/2631-7990/ad943f |
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| _version_ | 1850065387007246336 |
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| author | Huifeng Shao Pengcheng Xia Tao Zhang Jinyuan Shi Zhiqiang Huang Xianqi Yuan Zhiheng Nian Xiao Zhao Rougang Zhou Youping Gong Yong He |
| author_facet | Huifeng Shao Pengcheng Xia Tao Zhang Jinyuan Shi Zhiqiang Huang Xianqi Yuan Zhiheng Nian Xiao Zhao Rougang Zhou Youping Gong Yong He |
| author_sort | Huifeng Shao |
| collection | DOAJ |
| description | In clinical practice, the irregular shapes of traumas pose a significant challenge in rapidly manufacturing personalized scaffolds. To address these challenges, inspired by LEGO ^® bricks, this study proposed a novel concept of modular scaffolds and developed an innovative system based on machine vision for their rapid and intelligent assembly tailored to defect shapes. Trapezoidal interfaces effectively connect standardized bone units based on magnesium-doped silicate calcium, ensuring high stability of the modular scaffolds, with compressive strength up to 135 MPa and bending strength up to 17 MPa. Through self-developed defect recognition and reconstruction algorithms, defect recognition and personalized assembly schemes for bone scaffolds can be achieved autonomously. Modular scaffolds seamlessly integrate with surrounding bone tissue, promoting new bone growth, with no apparent differences compared to fully 3D printed integral scaffolds in the skull and femur repair experiments. In summary, the adoption of modular scaffolds not only integrates personalization and standardization but also satisfies the optimal treatment window. |
| format | Article |
| id | doaj-art-ba0da764c7b14db7b7b6c42fef01ea70 |
| institution | DOAJ |
| issn | 2631-7990 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | IOP Publishing |
| record_format | Article |
| series | International Journal of Extreme Manufacturing |
| spelling | doaj-art-ba0da764c7b14db7b7b6c42fef01ea702025-08-20T02:49:01ZengIOP PublishingInternational Journal of Extreme Manufacturing2631-79902024-01-017202550310.1088/2631-7990/ad943fModular scaffolds with intelligent visual guidance system for in situ bone tissue repairHuifeng Shao0Pengcheng Xia1Tao Zhang2Jinyuan Shi3Zhiqiang Huang4Xianqi Yuan5Zhiheng Nian6Xiao Zhao7Rougang Zhou8Youping Gong9Yong He10https://orcid.org/0000-0002-9099-0831School of Mechanical Engineering, Hangzhou Dianzi University , Hangzhou 310018, People’s Republic of ChinaDepartment of Orthopaedic Surgery, Institute of Digital Medicine, Nanjing First Hospital, Nanjing Medical University , Nanjing 210006, People’s Republic of ChinaSchool of Mechanical Engineering, Hangzhou Dianzi University , Hangzhou 310018, People’s Republic of ChinaSchool of Mechanical Engineering, Hangzhou Dianzi University , Hangzhou 310018, People’s Republic of ChinaSchool of Mechanical Engineering, Hangzhou Dianzi University , Hangzhou 310018, People’s Republic of ChinaSchool of Mechanical Engineering, Hangzhou Dianzi University , Hangzhou 310018, People’s Republic of ChinaSchool of Mechanical Engineering, Hangzhou Dianzi University , Hangzhou 310018, People’s Republic of ChinaDepartment of Orthopaedic Surgery, Institute of Digital Medicine, Nanjing First Hospital, Nanjing Medical University , Nanjing 210006, People’s Republic of ChinaSchool of Mechanical Engineering, Hangzhou Dianzi University , Hangzhou 310018, People’s Republic of ChinaSchool of Mechanical Engineering, Hangzhou Dianzi University , Hangzhou 310018, People’s Republic of ChinaState Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University , Hangzhou 310027, People’s Republic of ChinaIn clinical practice, the irregular shapes of traumas pose a significant challenge in rapidly manufacturing personalized scaffolds. To address these challenges, inspired by LEGO ^® bricks, this study proposed a novel concept of modular scaffolds and developed an innovative system based on machine vision for their rapid and intelligent assembly tailored to defect shapes. Trapezoidal interfaces effectively connect standardized bone units based on magnesium-doped silicate calcium, ensuring high stability of the modular scaffolds, with compressive strength up to 135 MPa and bending strength up to 17 MPa. Through self-developed defect recognition and reconstruction algorithms, defect recognition and personalized assembly schemes for bone scaffolds can be achieved autonomously. Modular scaffolds seamlessly integrate with surrounding bone tissue, promoting new bone growth, with no apparent differences compared to fully 3D printed integral scaffolds in the skull and femur repair experiments. In summary, the adoption of modular scaffolds not only integrates personalization and standardization but also satisfies the optimal treatment window.https://doi.org/10.1088/2631-7990/ad943f3D printingmodular scaffoldsrapidly manufacturingintelligent assemblytraumas repair |
| spellingShingle | Huifeng Shao Pengcheng Xia Tao Zhang Jinyuan Shi Zhiqiang Huang Xianqi Yuan Zhiheng Nian Xiao Zhao Rougang Zhou Youping Gong Yong He Modular scaffolds with intelligent visual guidance system for in situ bone tissue repair International Journal of Extreme Manufacturing 3D printing modular scaffolds rapidly manufacturing intelligent assembly traumas repair |
| title | Modular scaffolds with intelligent visual guidance system for in situ bone tissue repair |
| title_full | Modular scaffolds with intelligent visual guidance system for in situ bone tissue repair |
| title_fullStr | Modular scaffolds with intelligent visual guidance system for in situ bone tissue repair |
| title_full_unstemmed | Modular scaffolds with intelligent visual guidance system for in situ bone tissue repair |
| title_short | Modular scaffolds with intelligent visual guidance system for in situ bone tissue repair |
| title_sort | modular scaffolds with intelligent visual guidance system for in situ bone tissue repair |
| topic | 3D printing modular scaffolds rapidly manufacturing intelligent assembly traumas repair |
| url | https://doi.org/10.1088/2631-7990/ad943f |
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