Efficient biosynthesis of β-caryophyllene by engineered Yarrowia lipolytica

Efficient biosynthesis of β-caryophyllene by engineered Yarrowia lipolytica

Abstract Background β-Caryophyllene, a sesquiterpenoid, holds considerable potential in pharmaceutical, nutraceutical, cosmetic, and chemical industries. In order to overcome the limitation of β-caryophyllene production by the extraction from plants or chemical synthesis, we aimed the microbial prod...

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Main Authors: Young-Kyoung Park, Lucie Studena, Piotr Hapeta, Ramdane Haddouche, David J. Bell, Pablo Torres-Montero, Jose Luis Martinez, Jean-Marc Nicaud, Adriana Botes, Rodrigo Ledesma-Amaro
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Microbial Cell Factories
Subjects:
Β-caryophyllene
Yarrowia Lipolytica
Terpene
Bioproduction
Synthetic biology
Online Access:https://doi.org/10.1186/s12934-025-02660-w
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