MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing

Management of research-animal colonies is vital for lab productivity in preclinical research. Labs often rely on inefficient paper-based or spreadsheet-based methods to manage animal colonies. Dedicated software-based solutions are generally expensive and many lack remote access. Currently available...

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Main Authors: Robinson Vidva, Mir Abbas Raza, Jaswant Prabhakaran, Ayesha Sheikh, Alaina Sharp, Hayden Ott, Amelia Moore, Christopher Fleisher, Hailey Netherton, Evan Goldstein, Pothitos M. Pitychoutis, Tam V. Nguyen, Aaron Sathyanesan
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Computational and Structural Biotechnology Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S2001037025000261
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author Robinson Vidva
Mir Abbas Raza
Jaswant Prabhakaran
Ayesha Sheikh
Alaina Sharp
Hayden Ott
Amelia Moore
Christopher Fleisher
Hailey Netherton
Evan Goldstein
Pothitos M. Pitychoutis
Tam V. Nguyen
Aaron Sathyanesan
author_facet Robinson Vidva
Mir Abbas Raza
Jaswant Prabhakaran
Ayesha Sheikh
Alaina Sharp
Hayden Ott
Amelia Moore
Christopher Fleisher
Hailey Netherton
Evan Goldstein
Pothitos M. Pitychoutis
Tam V. Nguyen
Aaron Sathyanesan
author_sort Robinson Vidva
collection DOAJ
description Management of research-animal colonies is vital for lab productivity in preclinical research. Labs often rely on inefficient paper-based or spreadsheet-based methods to manage animal colonies. Dedicated software-based solutions are generally expensive and many lack remote access. Currently available open-source alternatives are difficult to implement and deploy. These solutions also do not have the capability to track ambient variables that affect colony well-being. We built MyVivarium, an open-source database management web application to address these gaps. MyVivarium can be easily deployed to the cloud and sustained for a cost comparable to starting and maintaining a lab website. Using MyVivarium, lab members can collaboratively track individual animals within a database. Physical identities of cages map onto the database using QR codes, enabling quick and easy record-keeping on mobile devices. Lab administrators can assign tasks to users with reminders for experiments or cage maintenance. Finally, we designed a low-cost system to sense ambient humidity, temperature, vivarium worker activity, and room illuminance. These data are then sent to MyVivarium in realtime providing information relevant to colony well-being. Taken together, MyVivarium is a novel, open-source, cloud-based application template that provides a low-cost, simple, and efficient way to digitally manage research-animal colonies.
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spelling doaj-art-ba0069101adf4b278777a2a0b6f0d5442025-02-09T05:00:01ZengElsevierComputational and Structural Biotechnology Journal2001-03702025-01-0127612623MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensingRobinson Vidva0Mir Abbas Raza1Jaswant Prabhakaran2Ayesha Sheikh3Alaina Sharp4Hayden Ott5Amelia Moore6Christopher Fleisher7Hailey Netherton8Evan Goldstein9Pothitos M. Pitychoutis10Tam V. Nguyen11Aaron Sathyanesan12Digirobi Solutions, Bengaluru, Karnataka, IndiaDepartment of Biology, College of Arts & Sciences, University of Dayton, Dayton, OH, USADepartment of Computer Science, College of Arts & Sciences, University of Dayton, Dayton, OH, USADepartment of Biology, College of Arts & Sciences, University of Dayton, Dayton, OH, USADepartment of Biology, College of Arts & Sciences, University of Dayton, Dayton, OH, USADepartment of Biology, College of Arts & Sciences, University of Dayton, Dayton, OH, USADepartment of Biology, College of Arts & Sciences, University of Dayton, Dayton, OH, USADepartment of Biology, College of Arts & Sciences, University of Dayton, Dayton, OH, USADepartment of Biological Sciences, College of Science & Mathematics, Augusta University, Augusta, GA, USA; Department of Neuroscience & Regenerative Medicine, Augusta University, Augusta, GA, USADepartment of Biological Sciences, College of Science & Mathematics, Augusta University, Augusta, GA, USA; Department of Neuroscience & Regenerative Medicine, Augusta University, Augusta, GA, USADepartment of Biology, College of Arts & Sciences, University of Dayton, Dayton, OH, USADepartment of Computer Science, College of Arts & Sciences, University of Dayton, Dayton, OH, USADepartment of Biology, College of Arts & Sciences, University of Dayton, Dayton, OH, USA; Department of Electrical and Computer Engineering, School of Engineering, University of Dayton, Dayton, OH, USA; Correspondence to: 300 College Park, Dayton, OH, USA.Management of research-animal colonies is vital for lab productivity in preclinical research. Labs often rely on inefficient paper-based or spreadsheet-based methods to manage animal colonies. Dedicated software-based solutions are generally expensive and many lack remote access. Currently available open-source alternatives are difficult to implement and deploy. These solutions also do not have the capability to track ambient variables that affect colony well-being. We built MyVivarium, an open-source database management web application to address these gaps. MyVivarium can be easily deployed to the cloud and sustained for a cost comparable to starting and maintaining a lab website. Using MyVivarium, lab members can collaboratively track individual animals within a database. Physical identities of cages map onto the database using QR codes, enabling quick and easy record-keeping on mobile devices. Lab administrators can assign tasks to users with reminders for experiments or cage maintenance. Finally, we designed a low-cost system to sense ambient humidity, temperature, vivarium worker activity, and room illuminance. These data are then sent to MyVivarium in realtime providing information relevant to colony well-being. Taken together, MyVivarium is a novel, open-source, cloud-based application template that provides a low-cost, simple, and efficient way to digitally manage research-animal colonies.http://www.sciencedirect.com/science/article/pii/S2001037025000261Mouse facilityOpen-source technologyIoT sensorsBiological database
spellingShingle Robinson Vidva
Mir Abbas Raza
Jaswant Prabhakaran
Ayesha Sheikh
Alaina Sharp
Hayden Ott
Amelia Moore
Christopher Fleisher
Hailey Netherton
Evan Goldstein
Pothitos M. Pitychoutis
Tam V. Nguyen
Aaron Sathyanesan
MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing
Computational and Structural Biotechnology Journal
Mouse facility
Open-source technology
IoT sensors
Biological database
title MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing
title_full MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing
title_fullStr MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing
title_full_unstemmed MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing
title_short MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing
title_sort myvivarium a cloud based lab animal colony management application with realtime ambient sensing
topic Mouse facility
Open-source technology
IoT sensors
Biological database
url http://www.sciencedirect.com/science/article/pii/S2001037025000261
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