Polygenic risk score models based on anxiety-related traits as endophenotypes to predict unipolar depression and suicidal behavior

Polygenic risk score models based on anxiety-related traits as endophenotypes to predict unipolar depression and suicidal behavior

The present study included the construction of polygenic risk score (PRS) models of individual differences in anxiety level, which increased values represent the endophenotype of depression and suicidal behavior, to predict these psychopathologies based on genotyping of 63 SNPs of serotoninergic, hy...

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Bibliographic Details
Main Authors: A. V. Kazantseva, R. F. Enikeeva, Yu. D. Davydova, R. G. Valinurov, I. Yu. Ahmerova I.Yu., S. B. Malykh, M. M. Lobaskova, E. K. Khusnutdinova
Format: Article
Language:Russian
Published: Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation 2019-12-01
Series:Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
Subjects:
depression, suicide, polygenic risk score, leukocyte telomere length
Online Access:https://www.bekhterevreview.com/jour/article/view/315
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