NLRP3, conveyed via extracellular vesicles from metabolic syndrome patients, is involved in atherosclerosis development

NLRP3, conveyed via extracellular vesicles from metabolic syndrome patients, is involved in atherosclerosis development

Abstract Background Inappropriate activation of the Nod-like receptor protein 3 (NLRP3)-inflammasome contributes to atherosclerosis progression and plaque instability in patients with cardiovascular events. However, its role in the atherosclerosis is not fully understood. We sought to uncover action...

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Main Authors: Xavier Vidal-Gómez, Luisa Vergori, Séverine Dubois, Frédéric Gagnadoux, Samir Henni, Reuben Veerapen, Olivier Meilhac, Mercedes Muñoz-Picos, Concepción Peiró, M. Carmen Martinez, Ramaroson Andriantsitohaina, on behalf of Metabol Study Group
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cell Communication and Signaling
Subjects:
NLRP3
Extracellular vesicles
Metabolic syndrome
Vascular inflammation
Atherosclerosis development
Online Access:https://doi.org/10.1186/s12964-025-02296-8
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