Alteration of 11β-Hydroxysteroid Dehydrogenase Type 1 and Glucocorticoid Receptor by Ethanol in Rat Liver and Mouse Hepatoma Cells
Alcohol is a potential risk factor of type 2 diabetes, but its underlying mechanism is unclear. To explore this issue, Wistar rats and mouse hepatoma cells (Hepa 1–6) were exposed to ethanol, 8 g·kg−1·d−1 for 3 months and 100 mM for 48 h, respectively. Glucose and insulin tolerance tests in vivo wer...
Saved in:
| Main Authors: | Zhaojie Meng, Xueying Bao, Ming Zhang, Shengnan Wei, Wenguang Chang, Jing Li, Li Chen, B. L. Grégoire Nyomba |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2013/218102 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Mast cells express 11β-hydroxysteroid dehydrogenase type 1: a role in restraining mast cell degranulation.
by: Agnes E Coutinho, et al.
Published: (2013-01-01) -
Deciphering 17-β-hydroxysteroid dehydrogenase 4: from molecular insights to cancer therapeutics
by: Meng-Bin Liao, et al.
Published: (2025-07-01) -
17β-Hydroxysteroid dehydrogenase type I and aromatase in ovarian cortical inclusion cysts
by: Enrique Pedernera, et al.
Published: (2025-03-01) -
Impact of isothiazolinone biocides on gonadal steroid production: Focus on 3β-hydroxysteroid dehydrogenase inhibition
by: Ke Zheng, et al.
Published: (2025-06-01) -
Regulation of 11β-hydroxysteroid dehydrogenase type 1 and 7α-hydroxylase CYP7B1 during social stress.
by: Martin Vodička, et al.
Published: (2014-01-01)