Primary Neuroendocrine Carcinoma of the Breast: Histopathological Criteria, Prognostic Factors, and Review of the Literature
We present here a case of a 42-year-old woman diagnosed with primary neuroendocrine carcinoma of the breast (NECB). We discuss the importance of histological criteria for primary neuroendocrine mammary carcinoma, established by WHO in 2003 and 2012. After an overview of different cases of primary ne...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2016/6762085 |
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| author | Lena Marinova Doroteya Malinova Snezhinka Vicheva |
| author_facet | Lena Marinova Doroteya Malinova Snezhinka Vicheva |
| author_sort | Lena Marinova |
| collection | DOAJ |
| description | We present here a case of a 42-year-old woman diagnosed with primary neuroendocrine carcinoma of the breast (NECB). We discuss the importance of histological criteria for primary neuroendocrine mammary carcinoma, established by WHO in 2003 and 2012. After an overview of different cases of primary neuroendocrine carcinoma of the breast published in the literature, we present information about differential diagnosis, prognostic factors, and surgical and adjuvant treatment. Prognosis of NECB is not different from that of other invasive breast carcinomas and the most important prognostic factor is tumor grade (G). There is no standard treatment and patients should be treated similarly to patients with invasive ductal carcinoma, NOS (not otherwise specified), whose choice of therapy depends on tumor’s size, degree of differentiation, clinical stage, and hormonal status. |
| format | Article |
| id | doaj-art-b9e0f982142b43289d8a3a1cc25854fd |
| institution | OA Journals |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-b9e0f982142b43289d8a3a1cc25854fd2025-08-20T02:19:19ZengWileyCase Reports in Pathology2090-67812090-679X2016-01-01201610.1155/2016/67620856762085Primary Neuroendocrine Carcinoma of the Breast: Histopathological Criteria, Prognostic Factors, and Review of the LiteratureLena Marinova0Doroteya Malinova1Snezhinka Vicheva2Department of Radiotherapy, Oncology Center, Varna, BulgariaDepartment of General and Clinical Pathology, Forensic Science and Deontology, Medical University, Varna, BulgariaDepartment of General and Clinical Pathology, Oncology Center, Varna, BulgariaWe present here a case of a 42-year-old woman diagnosed with primary neuroendocrine carcinoma of the breast (NECB). We discuss the importance of histological criteria for primary neuroendocrine mammary carcinoma, established by WHO in 2003 and 2012. After an overview of different cases of primary neuroendocrine carcinoma of the breast published in the literature, we present information about differential diagnosis, prognostic factors, and surgical and adjuvant treatment. Prognosis of NECB is not different from that of other invasive breast carcinomas and the most important prognostic factor is tumor grade (G). There is no standard treatment and patients should be treated similarly to patients with invasive ductal carcinoma, NOS (not otherwise specified), whose choice of therapy depends on tumor’s size, degree of differentiation, clinical stage, and hormonal status.http://dx.doi.org/10.1155/2016/6762085 |
| spellingShingle | Lena Marinova Doroteya Malinova Snezhinka Vicheva Primary Neuroendocrine Carcinoma of the Breast: Histopathological Criteria, Prognostic Factors, and Review of the Literature Case Reports in Pathology |
| title | Primary Neuroendocrine Carcinoma of the Breast: Histopathological Criteria, Prognostic Factors, and Review of the Literature |
| title_full | Primary Neuroendocrine Carcinoma of the Breast: Histopathological Criteria, Prognostic Factors, and Review of the Literature |
| title_fullStr | Primary Neuroendocrine Carcinoma of the Breast: Histopathological Criteria, Prognostic Factors, and Review of the Literature |
| title_full_unstemmed | Primary Neuroendocrine Carcinoma of the Breast: Histopathological Criteria, Prognostic Factors, and Review of the Literature |
| title_short | Primary Neuroendocrine Carcinoma of the Breast: Histopathological Criteria, Prognostic Factors, and Review of the Literature |
| title_sort | primary neuroendocrine carcinoma of the breast histopathological criteria prognostic factors and review of the literature |
| url | http://dx.doi.org/10.1155/2016/6762085 |
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