Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study
Background. Primary hyperparathyroidism (PHPT) and thyroid diseases are a frequent concomitant occurrence, but the surgical approach to associated disease is still debated. Methods. We retrospectively evaluated a series of PHPT patients focusing on thyroid disease and surgery. Results. Among 238 PHP...
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| Format: | Article |
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Wiley
2020-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2020/2182539 |
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| author | Elena Castellano Paolo Benso Roberto Attanasio Alberto Boriano Corrado Lauro Giorgio Borretta Felice Borghi |
| author_facet | Elena Castellano Paolo Benso Roberto Attanasio Alberto Boriano Corrado Lauro Giorgio Borretta Felice Borghi |
| author_sort | Elena Castellano |
| collection | DOAJ |
| description | Background. Primary hyperparathyroidism (PHPT) and thyroid diseases are a frequent concomitant occurrence, but the surgical approach to associated disease is still debated. Methods. We retrospectively evaluated a series of PHPT patients focusing on thyroid disease and surgery. Results. Among 238 PHPT patients undergoing parathyroidectomy (PTX) between 2002 and 2017, 128 were affected also by a benign thyroid disease, namely, goiter in 118 (76 multinodular (MNG) and 42 uninodular (UNG)), autoimmune thyroiditis in 10, and hyperthyroidism in 21. Surgical approach was unilateral neck exploration (UNE) in 59 patients and bilateral neck exploration (BNE) in 69. The PHPT cure rate was 94%. On comparing patients submitted to PTX only and PTX plus thyroidectomy (TX), in the latter MNG and hyperthyroidism were more frequent, and surgical time and length of stay were longer. No difference in surgical complications was found between patients undergoing UNE and BNE. Conclusion. PHPT patients with a concomitant thyroid disease underwent double surgery in almost two-thirds of the cases, mostly by BNE. The main factors driving the decision to perform concomitant PTX and TX were the presence of thyroid nodular disease with the nodule site ipsilateral to the presurgically localized parathyroid adenoma. |
| format | Article |
| id | doaj-art-b9d0f92d9d864c39b2c003f853c54b33 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-b9d0f92d9d864c39b2c003f853c54b332025-02-03T06:46:37ZengWileyInternational Journal of Endocrinology1687-83371687-83452020-01-01202010.1155/2020/21825392182539Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center StudyElena Castellano0Paolo Benso1Roberto Attanasio2Alberto Boriano3Corrado Lauro4Giorgio Borretta5Felice Borghi6Department of Endocrinology, Diabetes and Metabolism, Santa Croce and Carle Hospital, Cuneo, ItalyUnit of General and Oncological Surgery, Department of Surgery, Santa Croce and Carle Hospital, Cuneo, ItalyIRCCS Orthopedic Institute Galeazzi, Endocrinology Service, Milan, ItalyMedical Physics Department, Santa Croce and Carle Hospital, Cuneo, ItalyUnit of General and Oncological Surgery, Department of Surgery, Santa Croce and Carle Hospital, Cuneo, ItalyDepartment of Endocrinology, Diabetes and Metabolism, Santa Croce and Carle Hospital, Cuneo, ItalyUnit of General and Oncological Surgery, Department of Surgery, Santa Croce and Carle Hospital, Cuneo, ItalyBackground. Primary hyperparathyroidism (PHPT) and thyroid diseases are a frequent concomitant occurrence, but the surgical approach to associated disease is still debated. Methods. We retrospectively evaluated a series of PHPT patients focusing on thyroid disease and surgery. Results. Among 238 PHPT patients undergoing parathyroidectomy (PTX) between 2002 and 2017, 128 were affected also by a benign thyroid disease, namely, goiter in 118 (76 multinodular (MNG) and 42 uninodular (UNG)), autoimmune thyroiditis in 10, and hyperthyroidism in 21. Surgical approach was unilateral neck exploration (UNE) in 59 patients and bilateral neck exploration (BNE) in 69. The PHPT cure rate was 94%. On comparing patients submitted to PTX only and PTX plus thyroidectomy (TX), in the latter MNG and hyperthyroidism were more frequent, and surgical time and length of stay were longer. No difference in surgical complications was found between patients undergoing UNE and BNE. Conclusion. PHPT patients with a concomitant thyroid disease underwent double surgery in almost two-thirds of the cases, mostly by BNE. The main factors driving the decision to perform concomitant PTX and TX were the presence of thyroid nodular disease with the nodule site ipsilateral to the presurgically localized parathyroid adenoma.http://dx.doi.org/10.1155/2020/2182539 |
| spellingShingle | Elena Castellano Paolo Benso Roberto Attanasio Alberto Boriano Corrado Lauro Giorgio Borretta Felice Borghi Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study International Journal of Endocrinology |
| title | Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study |
| title_full | Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study |
| title_fullStr | Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study |
| title_full_unstemmed | Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study |
| title_short | Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study |
| title_sort | surgical approach to primary hyperparathyroidism in patients with concomitant thyroid diseases a retrospective single center study |
| url | http://dx.doi.org/10.1155/2020/2182539 |
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