Bilateral Primary Breast Cancer With Discordance in Molecular Subtypes: A Case Report
Molecular subtype is a crucial prognostic factor for bilateral breast cancer and plays a key role in guiding treatment decisions. Several studies have confirmed that the expression patterns of hormone receptor and human epidermal growth factor receptor 2 are generally consistent in synchronous bilat...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | International Journal of Breast Cancer |
| Online Access: | http://dx.doi.org/10.1155/ijbc/9082803 |
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| _version_ | 1849424547511533568 |
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| author | Yingying Rao Qian Zhan Hengyu Li |
| author_facet | Yingying Rao Qian Zhan Hengyu Li |
| author_sort | Yingying Rao |
| collection | DOAJ |
| description | Molecular subtype is a crucial prognostic factor for bilateral breast cancer and plays a key role in guiding treatment decisions. Several studies have confirmed that the expression patterns of hormone receptor and human epidermal growth factor receptor 2 are generally consistent in synchronous bilateral primary breast cancer. Discordance in the receptor expression status is commonly associated with poorer prognosis in synchronous bilateral breast cancer. However, there is currently limited literature reporting such cases. This article presents a case of synchronous bilateral primary breast cancer with discordant molecular subtypes and reviews relevant literature. |
| format | Article |
| id | doaj-art-b9cea96e582040faa1a73e963961371e |
| institution | Kabale University |
| issn | 2090-3189 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Breast Cancer |
| spelling | doaj-art-b9cea96e582040faa1a73e963961371e2025-08-20T03:30:08ZengWileyInternational Journal of Breast Cancer2090-31892025-01-01202510.1155/ijbc/9082803Bilateral Primary Breast Cancer With Discordance in Molecular Subtypes: A Case ReportYingying Rao0Qian Zhan1Hengyu Li2Department of Breast and Thyroid SurgeryDepartment of ImagingDepartment of Breast and Thyroid SurgeryMolecular subtype is a crucial prognostic factor for bilateral breast cancer and plays a key role in guiding treatment decisions. Several studies have confirmed that the expression patterns of hormone receptor and human epidermal growth factor receptor 2 are generally consistent in synchronous bilateral primary breast cancer. Discordance in the receptor expression status is commonly associated with poorer prognosis in synchronous bilateral breast cancer. However, there is currently limited literature reporting such cases. This article presents a case of synchronous bilateral primary breast cancer with discordant molecular subtypes and reviews relevant literature.http://dx.doi.org/10.1155/ijbc/9082803 |
| spellingShingle | Yingying Rao Qian Zhan Hengyu Li Bilateral Primary Breast Cancer With Discordance in Molecular Subtypes: A Case Report International Journal of Breast Cancer |
| title | Bilateral Primary Breast Cancer With Discordance in Molecular Subtypes: A Case Report |
| title_full | Bilateral Primary Breast Cancer With Discordance in Molecular Subtypes: A Case Report |
| title_fullStr | Bilateral Primary Breast Cancer With Discordance in Molecular Subtypes: A Case Report |
| title_full_unstemmed | Bilateral Primary Breast Cancer With Discordance in Molecular Subtypes: A Case Report |
| title_short | Bilateral Primary Breast Cancer With Discordance in Molecular Subtypes: A Case Report |
| title_sort | bilateral primary breast cancer with discordance in molecular subtypes a case report |
| url | http://dx.doi.org/10.1155/ijbc/9082803 |
| work_keys_str_mv | AT yingyingrao bilateralprimarybreastcancerwithdiscordanceinmolecularsubtypesacasereport AT qianzhan bilateralprimarybreastcancerwithdiscordanceinmolecularsubtypesacasereport AT hengyuli bilateralprimarybreastcancerwithdiscordanceinmolecularsubtypesacasereport |