Efficacy and safety of different proprotein convertase subtilisin/kexin type 9 inhibitors in the general population and solid organ transplant recipients: a network meta-analysis

Efficacy and safety of different proprotein convertase subtilisin/kexin type 9 inhibitors in the general population and solid organ transplant recipients: a network meta-analysis

IntroductionWe conducted a network meta-analysis (NMA) to compare the efficacy (primarily assessed by low-density lipoprotein cholesterol (LDL-C) reduction and cardiovascular event (CVE) incidence) and safety (total adverse events (AEs), neurocognitive events (NCEs), injection site reactions, infect...

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Bibliographic Details
Main Authors: Bohan Luo, Zhuang Sun, Han Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pharmacology
Subjects:
PCSK9 inhibitors
clinical efficacy
adverse reactions
mortality
meta-analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1584612/full
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