Metagenomic Next-Generation Sequencing (mNGS) for the Timely Diagnosis of Carbapenem-Resistant Klebsiella pneumoniae in Leukemia Patients
This report shows the contribution of metagenomic next-generation sequencing (mNGS) as an alternative to challenging diagnostic infection in immunosuppressed individuals. Herein, we report two leukemia patients who developed severe infections due to carbapenem-resistant Klebsiella pneumoniae (CrKP)....
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2022/6957028 |
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| _version_ | 1832568167800504320 |
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| author | Huan Tao Fang Hua Yingying Chen Yongqian Jia |
| author_facet | Huan Tao Fang Hua Yingying Chen Yongqian Jia |
| author_sort | Huan Tao |
| collection | DOAJ |
| description | This report shows the contribution of metagenomic next-generation sequencing (mNGS) as an alternative to challenging diagnostic infection in immunosuppressed individuals. Herein, we report two leukemia patients who developed severe infections due to carbapenem-resistant Klebsiella pneumoniae (CrKP). The mNGS can be strongly recommended as an alternative investigation for patients who are at high risk of infection without positivity on body fluid culture. This can provide the opportunity for adequate therapy. |
| format | Article |
| id | doaj-art-b9aea1febe1a48499e658205b11f4dfd |
| institution | Kabale University |
| issn | 2090-6633 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-b9aea1febe1a48499e658205b11f4dfd2025-02-03T00:59:36ZengWileyCase Reports in Infectious Diseases2090-66332022-01-01202210.1155/2022/6957028Metagenomic Next-Generation Sequencing (mNGS) for the Timely Diagnosis of Carbapenem-Resistant Klebsiella pneumoniae in Leukemia PatientsHuan Tao0Fang Hua1Yingying Chen2Yongqian Jia3Department of HematologyDepartment of HematologyDepartment of OncologyDepartment of HematologyThis report shows the contribution of metagenomic next-generation sequencing (mNGS) as an alternative to challenging diagnostic infection in immunosuppressed individuals. Herein, we report two leukemia patients who developed severe infections due to carbapenem-resistant Klebsiella pneumoniae (CrKP). The mNGS can be strongly recommended as an alternative investigation for patients who are at high risk of infection without positivity on body fluid culture. This can provide the opportunity for adequate therapy.http://dx.doi.org/10.1155/2022/6957028 |
| spellingShingle | Huan Tao Fang Hua Yingying Chen Yongqian Jia Metagenomic Next-Generation Sequencing (mNGS) for the Timely Diagnosis of Carbapenem-Resistant Klebsiella pneumoniae in Leukemia Patients Case Reports in Infectious Diseases |
| title | Metagenomic Next-Generation Sequencing (mNGS) for the Timely Diagnosis of Carbapenem-Resistant Klebsiella pneumoniae in Leukemia Patients |
| title_full | Metagenomic Next-Generation Sequencing (mNGS) for the Timely Diagnosis of Carbapenem-Resistant Klebsiella pneumoniae in Leukemia Patients |
| title_fullStr | Metagenomic Next-Generation Sequencing (mNGS) for the Timely Diagnosis of Carbapenem-Resistant Klebsiella pneumoniae in Leukemia Patients |
| title_full_unstemmed | Metagenomic Next-Generation Sequencing (mNGS) for the Timely Diagnosis of Carbapenem-Resistant Klebsiella pneumoniae in Leukemia Patients |
| title_short | Metagenomic Next-Generation Sequencing (mNGS) for the Timely Diagnosis of Carbapenem-Resistant Klebsiella pneumoniae in Leukemia Patients |
| title_sort | metagenomic next generation sequencing mngs for the timely diagnosis of carbapenem resistant klebsiella pneumoniae in leukemia patients |
| url | http://dx.doi.org/10.1155/2022/6957028 |
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