Molecular targets and mechanisms of cortex mori for lung cancer treatment: a network pharmacology study, molecular docking and in vitro and in vivo experimental validation

Molecular targets and mechanisms of cortex mori for lung cancer treatment: a network pharmacology study, molecular docking and in vitro and in vivo experimental validation

IntroductionThe cortex mori comes from the white endothelium of the young root of Morus alba L., and its medical value was first described in Shen Nong Ben Cao Jing (Classic on Materia Medical of Shennong). It was originally intended to purge lung, relieve asthma and reduce swelling. More and more s...

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Main Authors: Ying-Ying Shao, Qiu-Hong Yang, Shu-Fen He, Han-Bin Zhang, Wei-Chao Han, Bao-Cheng Xie, Rui-Rong He, Wen-Xin Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
lung cancer
cortex mori
network pharmacology
mechanism of action
target
pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1587856/full
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