Magnetocardiograph as a noninvasive and radiation-free diagnostic device for myocardial infarction: a systematic review and meta-analysis

Abstract. Background. This study aimed to evaluate the diagnostic accuracy of magnetocardiograph, a relatively new noninvasive device, in patients with myocardial infarction (MI). Methods. To identify studies assessing the diagnostic accuracy of magnetocardiography for MI, we searched four databases...

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Main Authors: Yansong Xu, Xiaole Han, Mingyue Guo, Ruochuan Li, Yiming Dong, Jiaxin Fan, Xiaofei Yin, Fei Xie, Jiaojiao Pang, Yuguo Chen
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2023-06-01
Series:Emergency and Critical Care Medicine
Online Access:http://journals.lww.com/10.1097/EC9.0000000000000085
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author Yansong Xu
Xiaole Han
Mingyue Guo
Ruochuan Li
Yiming Dong
Jiaxin Fan
Xiaofei Yin
Fei Xie
Jiaojiao Pang
Yuguo Chen
author_facet Yansong Xu
Xiaole Han
Mingyue Guo
Ruochuan Li
Yiming Dong
Jiaxin Fan
Xiaofei Yin
Fei Xie
Jiaojiao Pang
Yuguo Chen
author_sort Yansong Xu
collection DOAJ
description Abstract. Background. This study aimed to evaluate the diagnostic accuracy of magnetocardiograph, a relatively new noninvasive device, in patients with myocardial infarction (MI). Methods. To identify studies assessing the diagnostic accuracy of magnetocardiography for MI, we searched four databases on November 7, 2022, the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, and Web of Science, plus ClinicalTrials.gov. Three reviewers screened the studies independently and emailed the authors for more precise data when necessary. The Quality Assessment of Diagnostic Accuracy Studies 2 tool was used to evaluate the quality of the included studies. STATA (version 17; Stata Corporation, College Station, TX, USA) was used for meta-analysis of 2 × 2 contingency table data. Results. A total of 6 articles were included in this study. The diagnostic parameters of all included studies were summarized as follows: the pooled sensitivity was 0.91 (95% confidence intervals [95% CIs]: 0.81–0.96; I2 = 88.54); specificity was 0.83 (95% CI: 0.75–0.89; I2 = 83); positive likelihood ratio was 5.3 (95% CI: 3.5–8.2); negative likelihood ratio was 0.1 (95% CI: 0.04–0.24); and diagnostic odds ratio was 51 (95% CI: 16–161). The area under the curve for the receiver operating characteristic curve was 0.92 (95% CI: 0.89–0.94). After metaregression analysis, we found that the number of channels and the way of environmental magnetic noise elimination were heterogeneous sources. Conclusion. In summary, our meta-analysis shows that magnetocardiography holds a high accuracy in diagnosing MI and takes the advantages of noninvasive, radiation-free, and noncontact. However, further high-quality studies to confirm its usefulness in diagnosing MI are warranted.
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spelling doaj-art-b99bf3c19bff4c14bbad06bd3a58354f2025-08-20T01:54:12ZengWolters Kluwer Health/LWWEmergency and Critical Care Medicine2097-06172693-860X2023-06-0132707710.1097/EC9.0000000000000085202306000-00006Magnetocardiograph as a noninvasive and radiation-free diagnostic device for myocardial infarction: a systematic review and meta-analysisYansong Xu0Xiaole Han1Mingyue Guo2Ruochuan Li3Yiming Dong4Jiaxin Fan5Xiaofei Yin6Fei Xie7Jiaojiao Pang8Yuguo Chen9a Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, Shandong, Chinaf Key Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China.a Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, Shandong, Chinaa Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, Shandong, Chinaa Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, Shandong, Chinaa Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, Shandong, Chinaa Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, Shandong, Chinaa Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, Shandong, Chinaa Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, Shandong, Chinaa Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, Shandong, ChinaAbstract. Background. This study aimed to evaluate the diagnostic accuracy of magnetocardiograph, a relatively new noninvasive device, in patients with myocardial infarction (MI). Methods. To identify studies assessing the diagnostic accuracy of magnetocardiography for MI, we searched four databases on November 7, 2022, the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, and Web of Science, plus ClinicalTrials.gov. Three reviewers screened the studies independently and emailed the authors for more precise data when necessary. The Quality Assessment of Diagnostic Accuracy Studies 2 tool was used to evaluate the quality of the included studies. STATA (version 17; Stata Corporation, College Station, TX, USA) was used for meta-analysis of 2 × 2 contingency table data. Results. A total of 6 articles were included in this study. The diagnostic parameters of all included studies were summarized as follows: the pooled sensitivity was 0.91 (95% confidence intervals [95% CIs]: 0.81–0.96; I2 = 88.54); specificity was 0.83 (95% CI: 0.75–0.89; I2 = 83); positive likelihood ratio was 5.3 (95% CI: 3.5–8.2); negative likelihood ratio was 0.1 (95% CI: 0.04–0.24); and diagnostic odds ratio was 51 (95% CI: 16–161). The area under the curve for the receiver operating characteristic curve was 0.92 (95% CI: 0.89–0.94). After metaregression analysis, we found that the number of channels and the way of environmental magnetic noise elimination were heterogeneous sources. Conclusion. In summary, our meta-analysis shows that magnetocardiography holds a high accuracy in diagnosing MI and takes the advantages of noninvasive, radiation-free, and noncontact. However, further high-quality studies to confirm its usefulness in diagnosing MI are warranted.http://journals.lww.com/10.1097/EC9.0000000000000085
spellingShingle Yansong Xu
Xiaole Han
Mingyue Guo
Ruochuan Li
Yiming Dong
Jiaxin Fan
Xiaofei Yin
Fei Xie
Jiaojiao Pang
Yuguo Chen
Magnetocardiograph as a noninvasive and radiation-free diagnostic device for myocardial infarction: a systematic review and meta-analysis
Emergency and Critical Care Medicine
title Magnetocardiograph as a noninvasive and radiation-free diagnostic device for myocardial infarction: a systematic review and meta-analysis
title_full Magnetocardiograph as a noninvasive and radiation-free diagnostic device for myocardial infarction: a systematic review and meta-analysis
title_fullStr Magnetocardiograph as a noninvasive and radiation-free diagnostic device for myocardial infarction: a systematic review and meta-analysis
title_full_unstemmed Magnetocardiograph as a noninvasive and radiation-free diagnostic device for myocardial infarction: a systematic review and meta-analysis
title_short Magnetocardiograph as a noninvasive and radiation-free diagnostic device for myocardial infarction: a systematic review and meta-analysis
title_sort magnetocardiograph as a noninvasive and radiation free diagnostic device for myocardial infarction a systematic review and meta analysis
url http://journals.lww.com/10.1097/EC9.0000000000000085
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