Dap10 co-stimulation enhances the anti-HCC efficacy of NKp30 chimeric antigen receptor T cells

Chimeric antigen receptor (CAR) T-cell immunotherapy has made significant breakthroughs in the treatment of relapsed or refractory hematologic malignancies, but its efficacy in solid tumors remains limited. In this study, we developed a chimeric NKp30 (chNKp30) receptor whose ligand, B7H6, is often...

Full description

Saved in:
Bibliographic Details
Main Authors: JieYu Li, LiMei Chen, MingShui Chen, Miao Lin, Zineng Xie, HuiLing Wu, ZhiFeng Zhou, WanSong Lin
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Translational Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325001561
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items