Towards Metabolic Organic Radical Contrast Agents (mORCAs) for Magnetic Resonance Imaging
We report two conjugates of <i>gem</i>-diethyl pyrroline nitroxide radicals with D-mannosamine as potential metabolic organic radical contrast agents, mORCAs, circumventing the need for biorthogonal reactions. In-cell EPR spectroscopy, using Jurkat cells and analogous conjugate, based on...
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| Main Authors: | Shuyang Zhang, Sabina Dhakal, Evan Curtis, Hunter Miller, Joseph T. Paletta, Connor Gee, Suchada Rajca, Forrest Kievit, Andrzej Rajca |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-04-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/30/7/1581 |
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