Molecular breeding of farm animals through gene editing
The rapid development of biotechnology has facilitated our understanding of the biological functions of candidate genes for important economic traits in farm animals. Molecular breeding by gene editing has greatly revolutionized the breeding of farm animals. Through gene editing and embryo manipulat...
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| Format: | Article |
| Language: | English |
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Science Press
2023-07-01
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| Series: | National Science Open |
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| Online Access: | https://www.sciengine.com/doi/10.1360/nso/20220066 |
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| author | Gao Fei Hou Naipeng Du Xuguang Wang Yu Zhao Jianguo Wu Sen |
| author_facet | Gao Fei Hou Naipeng Du Xuguang Wang Yu Zhao Jianguo Wu Sen |
| author_sort | Gao Fei |
| collection | DOAJ |
| description | The rapid development of biotechnology has facilitated our understanding of the biological functions of candidate genes for important economic traits in farm animals. Molecular breeding by gene editing has greatly revolutionized the breeding of farm animals. Through gene editing and embryo manipulation, breeds with designed economic or disease-resistant traits can be readily generated. Along with this fast progress, the safety assessment of gene-edited farm animals has attracted public and regulatory attention. This review summarizes the research progress of gene editing in farm animals, focusing on performance improvement, disease resistance, bioreactors, animal welfare, and environmental friendliness. The limitations and future development of gene editing technology in farm animal breeding are also discussed. |
| format | Article |
| id | doaj-art-b9926faddc3f429e8562548fe72c4a51 |
| institution | DOAJ |
| issn | 2097-1168 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | Science Press |
| record_format | Article |
| series | National Science Open |
| spelling | doaj-art-b9926faddc3f429e8562548fe72c4a512025-08-20T02:47:08ZengScience PressNational Science Open2097-11682023-07-01210.1360/nso/20220066eb33e642Molecular breeding of farm animals through gene editingGao Fei0Hou Naipeng1Du Xuguang2Wang Yu3Zhao Jianguo4Wu Sen5["State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing 100193, China","Sanya Institute of China Agricultural University, Sanya 572025, China"]["College of Animal Science and Technology, China Agricultural University, Beijing 100193, China","Sanya Institute of China Agricultural University, Sanya 572025, China"]["State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing 100193, China","Sanya Institute of China Agricultural University, Sanya 572025, China"]["Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China"]["Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China"]["State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing 100193, China","Sanya Institute of China Agricultural University, Sanya 572025, China"]The rapid development of biotechnology has facilitated our understanding of the biological functions of candidate genes for important economic traits in farm animals. Molecular breeding by gene editing has greatly revolutionized the breeding of farm animals. Through gene editing and embryo manipulation, breeds with designed economic or disease-resistant traits can be readily generated. Along with this fast progress, the safety assessment of gene-edited farm animals has attracted public and regulatory attention. This review summarizes the research progress of gene editing in farm animals, focusing on performance improvement, disease resistance, bioreactors, animal welfare, and environmental friendliness. The limitations and future development of gene editing technology in farm animal breeding are also discussed.https://www.sciengine.com/doi/10.1360/nso/20220066molecular breedingfarm animalsgene editing |
| spellingShingle | Gao Fei Hou Naipeng Du Xuguang Wang Yu Zhao Jianguo Wu Sen Molecular breeding of farm animals through gene editing National Science Open molecular breeding farm animals gene editing |
| title | Molecular breeding of farm animals through gene editing |
| title_full | Molecular breeding of farm animals through gene editing |
| title_fullStr | Molecular breeding of farm animals through gene editing |
| title_full_unstemmed | Molecular breeding of farm animals through gene editing |
| title_short | Molecular breeding of farm animals through gene editing |
| title_sort | molecular breeding of farm animals through gene editing |
| topic | molecular breeding farm animals gene editing |
| url | https://www.sciengine.com/doi/10.1360/nso/20220066 |
| work_keys_str_mv | AT gaofei molecularbreedingoffarmanimalsthroughgeneediting AT hounaipeng molecularbreedingoffarmanimalsthroughgeneediting AT duxuguang molecularbreedingoffarmanimalsthroughgeneediting AT wangyu molecularbreedingoffarmanimalsthroughgeneediting AT zhaojianguo molecularbreedingoffarmanimalsthroughgeneediting AT wusen molecularbreedingoffarmanimalsthroughgeneediting |