Pediatric sepsis phenotypes for enhanced therapeutics: An application of clustering to electronic health records

Abstract Objective The heterogeneity of pediatric sepsis patients suggests the potential benefits of clustering analytics to derive phenotypes with distinct host response patterns that may help guide personalized therapeutics. We evaluate the relative performance of latent class analysis (LCA) and K...

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Bibliographic Details
Main Authors: Ioannis Koutroulis, Tom Velez, Tony Wang, Seife Yohannes, Jessica E. Galarraga, Joseph A. Morales, Robert J. Freishtat, James M. Chamberlain
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Journal of the American College of Emergency Physicians Open
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Online Access:https://doi.org/10.1002/emp2.12660
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