Molecular characterization of swine acute diarrhea syndrome coronavirus detected in Vietnamese pigs

Abstract Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a novel porcine coronavirus that was recently identified in southern China in 2017. At present, there is a lack of nationwide epidemiological investigations of the newly emerged SADS-CoV. Because Vietnam is geographically adjacent to s...

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Bibliographic Details
Main Authors: Nam Phuong Le, Bac Tran Le, Van Phan Le, Jung-Eun Park
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Veterinary Research
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Online Access:https://doi.org/10.1186/s13567-024-01445-0
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Summary:Abstract Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a novel porcine coronavirus that was recently identified in southern China in 2017. At present, there is a lack of nationwide epidemiological investigations of the newly emerged SADS-CoV. Because Vietnam is geographically adjacent to southern China, many diseases have spread from China to Vietnam. To assess SADS-CoV transmission to Vietnam, we conducted a retrospective study to detect SADS-CoV in samples collected from pig farms in northern Vietnam. Among the 69 fecal samples tested, 5 were positive for SADS-CoV. The spike gene sequence showed high genetic homology with strains circulating in China. Our study is the first to show that SADS-CoV has spread from China to Vietnam and highlights the need for global epidemiological investigations of SADS-CoV.
ISSN:1297-9716