The effect of immunomodulatory celecoxsib on the gene expression of inhibitory receptors in dendritic cells generated from monocyte cells

The effect of immunomodulatory celecoxsib on the gene expression of inhibitory receptors in dendritic cells generated from monocyte cells

Abstract Autoimmune diseases are characterized by irregular immune responses that disrupt self-tolerance. This research explores the effects of the immunomodulatory drug celecoxib on the expression of immune checkpoint receptors in monocyte-derived dendritic cells (DCs). Key receptors, including CTL...

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Bibliographic Details
Main Authors: Vida Hashemi, Behzad Baradaran, Bahar Naseri, Javad Masoumi, Elham Baghbani, Nazila Alizadeh, Reza Shiri Haris, Arezoo Hosseini
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Research Notes
Subjects:
Celecoxib
Immune checkpoint
Tolerogenic dendritic cell
Autoimmune diseases
Online Access:https://doi.org/10.1186/s13104-025-07226-y
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