<i>Tityus serrulatus</i> Scorpion Venom-Induced Nociceptive Responses Depend on TRPV1, Immune Cells, and Pro-Inflammatory Cytokines

<i>Tityus serrulatus</i> Scorpion Venom-Induced Nociceptive Responses Depend on TRPV1, Immune Cells, and Pro-Inflammatory Cytokines

For centuries, researchers have been fascinated by the composition of scorpion venom and its local and systemic effects on humans. During a sting, scorpions inject peptides and proteins that can affect immune cells and neurons. While the immune and nervous systems have been studied independently in...

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Bibliographic Details
Main Authors: Camila R. Ferraz, Marília F. Manchope, Mariana M. Bertozzi, Telma Saraiva-Santos, Ketlem C. Andrade, Anelise Franciosi, Tiago H. Zaninelli, Julia Bagatim-Souza, Sergio M. Borghi, Denise M. Cândido, Thiago M. Cunha, Rubia Casagrande, Fábio H. Kwasniewski, Waldiceu A. Verri
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Toxins
Subjects:
<i>Tityus serrulatus</i>
hyperalgesia
pain
neuroinflammation
TNF-α
IL-1β
Online Access:https://www.mdpi.com/2072-6651/17/7/332
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