The impact of remimazolam sedation during neuraxial anesthesia on perioperative cognitive function in elderly patients: a multicenter randomized controlled study

The impact of remimazolam sedation during neuraxial anesthesia on perioperative cognitive function in elderly patients: a multicenter randomized controlled study

BackgroundRemimazolam, a novel ultra-short-acting benzodiazepine, is a potential sedative for non-general anesthesia surgery in the elderly. This study aimed to investigate the appropriate sedative dosage of remimazolam and its effects on perioperative cognitive function in elderly patients undergoi...

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Main Authors: Dan Qiao, Jia-Min Kang, Rui Zhang, Lin-Yue Zong, Ying Xu, Wei-Wei Zhang, Qi Zhou, Yan Li, Tao Han, Yue-Ming Zhang, Li-Jun Yin, Jin Xu, Shou-Shi Wang, Yuan Yuan, Qing Li, Kai-Jun Niu, Yu-Xin Zheng, Lin-Lin Zhang, Yi-Ze Li, Yong-Hao Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
remimazolam
sedation
neuraxial anesthesia
postoperative cognitive complications
cognitive function
elderly
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1504813/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1504813/full

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