Exploring Natural Deep Eutectic Solvents (NADES) for Enhanced Essential Oil Extraction: Current Insights and Applications

Essential oils (EOs) are highly valued in the cosmetic and food industries for their diverse properties. However, traditional extraction methods often result in low yields, inconsistent compositions, lengthy extraction times, and the use of potentially harmful solvents. Natural deep eutectic solvent...

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Main Authors: Luis Acosta-Vega, Alejandro Cifuentes, Elena Ibáñez, Paula Galeano Garcia
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/2/284
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author Luis Acosta-Vega
Alejandro Cifuentes
Elena Ibáñez
Paula Galeano Garcia
author_facet Luis Acosta-Vega
Alejandro Cifuentes
Elena Ibáñez
Paula Galeano Garcia
author_sort Luis Acosta-Vega
collection DOAJ
description Essential oils (EOs) are highly valued in the cosmetic and food industries for their diverse properties. However, traditional extraction methods often result in low yields, inconsistent compositions, lengthy extraction times, and the use of potentially harmful solvents. Natural deep eutectic solvents (NADES) have emerged as promising alternatives, offering advantages such as higher efficiency, cost-effectiveness, biodegradability, and tunable properties. This review explores the application of NADES in enhancing EO extraction, focusing on current methodologies, key insights, and practical applications. It examines the factors that influence EO extraction with NADES, including the optimization of their physicochemical properties, extraction techniques, operational conditions, and the role of sample pretreatment in improving efficiency. Additionally, this review covers the chemical characterization and biological activities of EOs extracted using NADES. By providing a comprehensive overview, it highlights the potential of NADES to improve EO extraction and suggests directions for future research in this field.
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series Molecules
spelling doaj-art-b961f517ae7a48ed82c4c4854baf358c2025-01-24T13:43:25ZengMDPI AGMolecules1420-30492025-01-0130228410.3390/molecules30020284Exploring Natural Deep Eutectic Solvents (NADES) for Enhanced Essential Oil Extraction: Current Insights and ApplicationsLuis Acosta-Vega0Alejandro Cifuentes1Elena Ibáñez2Paula Galeano Garcia3Grupo de Investigación en Productos Naturales Amazónicos (GIPRONAZ), Facultad de Ciencias Básicas, Universidad de la Amazonia, Florencia 180001, ColombiaLaboratory of Foodomics, Institute of Food Science Research, CIAL, CSIC, Nicolás Cabrera 9, 28049 Madrid, SpainLaboratory of Foodomics, Institute of Food Science Research, CIAL, CSIC, Nicolás Cabrera 9, 28049 Madrid, SpainGrupo de Investigación en Productos Naturales Amazónicos (GIPRONAZ), Facultad de Ciencias Básicas, Universidad de la Amazonia, Florencia 180001, ColombiaEssential oils (EOs) are highly valued in the cosmetic and food industries for their diverse properties. However, traditional extraction methods often result in low yields, inconsistent compositions, lengthy extraction times, and the use of potentially harmful solvents. Natural deep eutectic solvents (NADES) have emerged as promising alternatives, offering advantages such as higher efficiency, cost-effectiveness, biodegradability, and tunable properties. This review explores the application of NADES in enhancing EO extraction, focusing on current methodologies, key insights, and practical applications. It examines the factors that influence EO extraction with NADES, including the optimization of their physicochemical properties, extraction techniques, operational conditions, and the role of sample pretreatment in improving efficiency. Additionally, this review covers the chemical characterization and biological activities of EOs extracted using NADES. By providing a comprehensive overview, it highlights the potential of NADES to improve EO extraction and suggests directions for future research in this field.https://www.mdpi.com/1420-3049/30/2/284NADESessential oilscholine chloridevolatile compoundsGC-MS
spellingShingle Luis Acosta-Vega
Alejandro Cifuentes
Elena Ibáñez
Paula Galeano Garcia
Exploring Natural Deep Eutectic Solvents (NADES) for Enhanced Essential Oil Extraction: Current Insights and Applications
Molecules
NADES
essential oils
choline chloride
volatile compounds
GC-MS
title Exploring Natural Deep Eutectic Solvents (NADES) for Enhanced Essential Oil Extraction: Current Insights and Applications
title_full Exploring Natural Deep Eutectic Solvents (NADES) for Enhanced Essential Oil Extraction: Current Insights and Applications
title_fullStr Exploring Natural Deep Eutectic Solvents (NADES) for Enhanced Essential Oil Extraction: Current Insights and Applications
title_full_unstemmed Exploring Natural Deep Eutectic Solvents (NADES) for Enhanced Essential Oil Extraction: Current Insights and Applications
title_short Exploring Natural Deep Eutectic Solvents (NADES) for Enhanced Essential Oil Extraction: Current Insights and Applications
title_sort exploring natural deep eutectic solvents nades for enhanced essential oil extraction current insights and applications
topic NADES
essential oils
choline chloride
volatile compounds
GC-MS
url https://www.mdpi.com/1420-3049/30/2/284
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AT elenaibanez exploringnaturaldeepeutecticsolventsnadesforenhancedessentialoilextractioncurrentinsightsandapplications
AT paulagaleanogarcia exploringnaturaldeepeutecticsolventsnadesforenhancedessentialoilextractioncurrentinsightsandapplications