Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation
Abstract Background The effect of revascularization by PCI for acute coronary syndrome (ACS) on the severity of ischemic mitral regurge (IMR) is still unclear. Objective To evaluate the effect of successful total revascularization by PCI for ACS on the degree of IMR. Methods A total of 240 patients...
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Springer
2018-09-01
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| Series: | Egyptian Journal of Critical Care Medicine |
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| Online Access: | https://doi.org/10.1016/j.ejccm.2018.02.001 |
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| author | Hazem El-Akabawy Hamdy Abdul Azeem EL-Shazly Abdul Khalek |
| author_facet | Hazem El-Akabawy Hamdy Abdul Azeem EL-Shazly Abdul Khalek |
| author_sort | Hazem El-Akabawy |
| collection | DOAJ |
| description | Abstract Background The effect of revascularization by PCI for acute coronary syndrome (ACS) on the severity of ischemic mitral regurge (IMR) is still unclear. Objective To evaluate the effect of successful total revascularization by PCI for ACS on the degree of IMR. Methods A total of 240 patients presenting with ACS for the first time were studied by this an open-label, multicenter, prospective clinical trial between July 2015 to February 2017. All patients were subjected for clinical assessment, transthoracic echocardiographic assessment and coronary angiography. The patients divided into two groups: group A; those who had undergone successful total revascularization of a significant coronary artery disease using PCI, and group B; those who had optimal medical treatment with no total revascularization, failed PCI or for CABG. Group A patients subdivided into subgroup I, patients with improvement of the IMR; and subgroup II, patients with no improvement of IMR. Results Only 65% of the patients showed IMR and 149 of them underwent successful complete revascularization by PCI; 68% of them showed IMR improvement and 32% showed no improvement. There was a significant improvement of the IMR degree after total revascularization by PCI. Moreover, this improvement was significant in subgroup I (p < 0.001). Percutaneous coronary intervention, EF and SWMI were significant predictors of IMR improvement following successful complete revascularization. Conclusion Successful total revascularization by early PCI improve IMR degree. |
| format | Article |
| id | doaj-art-b960cf4dd5ef4e988cab343f86100ba7 |
| institution | DOAJ |
| issn | 2090-7303 2090-9209 |
| language | English |
| publishDate | 2018-09-01 |
| publisher | Springer |
| record_format | Article |
| series | Egyptian Journal of Critical Care Medicine |
| spelling | doaj-art-b960cf4dd5ef4e988cab343f86100ba72025-08-20T03:04:18ZengSpringerEgyptian Journal of Critical Care Medicine2090-73032090-92092018-09-0162253110.1016/j.ejccm.2018.02.001Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitationHazem El-Akabawy0Hamdy Abdul Azeem1EL-Shazly Abdul Khalek2Critical Care Medicine Department, Kasr Alaini, Cairo UniversityCardiology Department, Al Azhar UniversityCardiology Department, Al Azhar UniversityAbstract Background The effect of revascularization by PCI for acute coronary syndrome (ACS) on the severity of ischemic mitral regurge (IMR) is still unclear. Objective To evaluate the effect of successful total revascularization by PCI for ACS on the degree of IMR. Methods A total of 240 patients presenting with ACS for the first time were studied by this an open-label, multicenter, prospective clinical trial between July 2015 to February 2017. All patients were subjected for clinical assessment, transthoracic echocardiographic assessment and coronary angiography. The patients divided into two groups: group A; those who had undergone successful total revascularization of a significant coronary artery disease using PCI, and group B; those who had optimal medical treatment with no total revascularization, failed PCI or for CABG. Group A patients subdivided into subgroup I, patients with improvement of the IMR; and subgroup II, patients with no improvement of IMR. Results Only 65% of the patients showed IMR and 149 of them underwent successful complete revascularization by PCI; 68% of them showed IMR improvement and 32% showed no improvement. There was a significant improvement of the IMR degree after total revascularization by PCI. Moreover, this improvement was significant in subgroup I (p < 0.001). Percutaneous coronary intervention, EF and SWMI were significant predictors of IMR improvement following successful complete revascularization. Conclusion Successful total revascularization by early PCI improve IMR degree.https://doi.org/10.1016/j.ejccm.2018.02.001Ischemic mitral regurgeTotal revascularizationAcute coronary syndromePercutaneous coronary interventionMyocardial infarctionEchocardiography |
| spellingShingle | Hazem El-Akabawy Hamdy Abdul Azeem EL-Shazly Abdul Khalek Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation Egyptian Journal of Critical Care Medicine Ischemic mitral regurge Total revascularization Acute coronary syndrome Percutaneous coronary intervention Myocardial infarction Echocardiography |
| title | Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation |
| title_full | Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation |
| title_fullStr | Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation |
| title_full_unstemmed | Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation |
| title_short | Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation |
| title_sort | short term effect of percutaneous coronary intervention on ischemic mitral regurgitation |
| topic | Ischemic mitral regurge Total revascularization Acute coronary syndrome Percutaneous coronary intervention Myocardial infarction Echocardiography |
| url | https://doi.org/10.1016/j.ejccm.2018.02.001 |
| work_keys_str_mv | AT hazemelakabawy shorttermeffectofpercutaneouscoronaryinterventiononischemicmitralregurgitation AT hamdyabdulazeem shorttermeffectofpercutaneouscoronaryinterventiononischemicmitralregurgitation AT elshazlyabdulkhalek shorttermeffectofpercutaneouscoronaryinterventiononischemicmitralregurgitation |