Treatment of pseudophakic aqueous misdirection syndrome
Abstract To describe the management and clinical course of 12 cases of pseudophakic aqueous misdirection syndrome (AMS). Twelve eyes of 12 Patients diagnosed with pseudophakic AMS between 2021 and 2022 were included. Best-corrected visual acuity, refraction, intraocular pressure (IOP), anti-glaucoma...
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Nature Portfolio
2025-01-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-024-83659-y |
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| author | Joel-Benjamin Lincke Nathanael Häner Megir Schawkat Martin S. Zinkernagel Jan Darius Unterlauft |
| author_facet | Joel-Benjamin Lincke Nathanael Häner Megir Schawkat Martin S. Zinkernagel Jan Darius Unterlauft |
| author_sort | Joel-Benjamin Lincke |
| collection | DOAJ |
| description | Abstract To describe the management and clinical course of 12 cases of pseudophakic aqueous misdirection syndrome (AMS). Twelve eyes of 12 Patients diagnosed with pseudophakic AMS between 2021 and 2022 were included. Best-corrected visual acuity, refraction, intraocular pressure (IOP), anti-glaucomatous medication, spectral domain ocular coherence tomography (SD-OCT) and postoperative complications were evaluated. The mean time of AMS onset was 888 days (SD ± 1210, range: 1–2920) after cataract surgery. Treatment with IOP-lowering medication alone was non-sufficient in all followed cases. Laser iridotomy (LIT) was performed in 4 eyes and led to resolution of AMS in 3 eyes. Nine eyes were treated surgically with 23-gauge pars plana vitrectomy and irido-zonulectomy. The most common postsurgical complication was cystoid macular edema (CME), occurring in 30% of cases. AMS is a rare but serious complication after cataract surgery, which can occur many years later. While LIT can be tried as first line treatment, pars plana vitrectomy with irido-zonulectomy is often required to ultimately control IOP in these eyes. A common complication after vitrectomy is CME. |
| format | Article |
| id | doaj-art-b95e44e725bf42bfb89b1a850e50b304 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj-art-b95e44e725bf42bfb89b1a850e50b3042025-01-12T12:14:50ZengNature PortfolioScientific Reports2045-23222025-01-011511610.1038/s41598-024-83659-yTreatment of pseudophakic aqueous misdirection syndromeJoel-Benjamin Lincke0Nathanael Häner1Megir Schawkat2Martin S. Zinkernagel3Jan Darius Unterlauft4Department of Ophthalmology, Inselspital, Bern University Hospital, University of BernDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of BernDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of BernDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of BernDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of BernAbstract To describe the management and clinical course of 12 cases of pseudophakic aqueous misdirection syndrome (AMS). Twelve eyes of 12 Patients diagnosed with pseudophakic AMS between 2021 and 2022 were included. Best-corrected visual acuity, refraction, intraocular pressure (IOP), anti-glaucomatous medication, spectral domain ocular coherence tomography (SD-OCT) and postoperative complications were evaluated. The mean time of AMS onset was 888 days (SD ± 1210, range: 1–2920) after cataract surgery. Treatment with IOP-lowering medication alone was non-sufficient in all followed cases. Laser iridotomy (LIT) was performed in 4 eyes and led to resolution of AMS in 3 eyes. Nine eyes were treated surgically with 23-gauge pars plana vitrectomy and irido-zonulectomy. The most common postsurgical complication was cystoid macular edema (CME), occurring in 30% of cases. AMS is a rare but serious complication after cataract surgery, which can occur many years later. While LIT can be tried as first line treatment, pars plana vitrectomy with irido-zonulectomy is often required to ultimately control IOP in these eyes. A common complication after vitrectomy is CME.https://doi.org/10.1038/s41598-024-83659-yAqueous misdirection syndromeMalignant glaucomaCystoid macular edema |
| spellingShingle | Joel-Benjamin Lincke Nathanael Häner Megir Schawkat Martin S. Zinkernagel Jan Darius Unterlauft Treatment of pseudophakic aqueous misdirection syndrome Scientific Reports Aqueous misdirection syndrome Malignant glaucoma Cystoid macular edema |
| title | Treatment of pseudophakic aqueous misdirection syndrome |
| title_full | Treatment of pseudophakic aqueous misdirection syndrome |
| title_fullStr | Treatment of pseudophakic aqueous misdirection syndrome |
| title_full_unstemmed | Treatment of pseudophakic aqueous misdirection syndrome |
| title_short | Treatment of pseudophakic aqueous misdirection syndrome |
| title_sort | treatment of pseudophakic aqueous misdirection syndrome |
| topic | Aqueous misdirection syndrome Malignant glaucoma Cystoid macular edema |
| url | https://doi.org/10.1038/s41598-024-83659-y |
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