Soufeng sanjie formula alleviates bone erosion in CIA mice via inhibiting RANKL/NF-κB signaling pathway and ameliorates the RA symptom in patients

Soufeng sanjie formula alleviates bone erosion in CIA mice via inhibiting RANKL/NF-κB signaling pathway and ameliorates the RA symptom in patients

Aim of the studySoufeng sanjie formula (SF), composed by scolopendra, scorpion, astragali radix and black soybean seed coats, is an in-hospital preparation of traditional Chinese medicine used for the treatment of rheumatoid arthritis (RA). It has been demonstrated to have a prominent effect on reli...

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Bibliographic Details
Main Authors: Dan Lin, Yutong Wu, Lizhong Zhu, Jie Yang, Jianbin Ge, Xiaoyan Sun, Xueting Cai, Juan Ye, Zhonghua Pang, Jiao Chen, Chunping Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
Soufeng sanjie formula
rheumatoid arthritis
bone erosion
osteoclast
RANKL/NF-κB
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1604180/full
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