Subjective cognitive deficits and its correlates among patients with bipolar disorder: Findings from the bipolar disorder course and outcome study from India (BiD-CoIN study)
Aim: This study aimed to evaluate the prevalence of subjective cognitive complaints and their association with clinical variables, insight, and disability. Methodology: Seven hundred and seventy-three subjects with bipolar disorder (BD), recruited across 14 centers, currently in the euthymic phase w...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2023-03-01
|
| Series: | Indian Journal of Psychiatry |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/indianjpsychiatry.indianjpsychiatry_367_22 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832593640647557120 |
|---|---|
| author | Sandeep Grover Ajit Avasthi Rahul Chakravarty Amitava Dan Kaustav Chakraborty Rajarshi Neogi Avinash Desouza Omkar Nayak Samir Praharaj Vikas Menon Raman Deep Manish Bathla Alka A. Subramanyam Naresh Nebhinani Prosenjit Ghosh Bhavesh Lakdawala Ranjan Bhattacharya |
| author_facet | Sandeep Grover Ajit Avasthi Rahul Chakravarty Amitava Dan Kaustav Chakraborty Rajarshi Neogi Avinash Desouza Omkar Nayak Samir Praharaj Vikas Menon Raman Deep Manish Bathla Alka A. Subramanyam Naresh Nebhinani Prosenjit Ghosh Bhavesh Lakdawala Ranjan Bhattacharya |
| author_sort | Sandeep Grover |
| collection | DOAJ |
| description | Aim:
This study aimed to evaluate the prevalence of subjective cognitive complaints and their association with clinical variables, insight, and disability.
Methodology:
Seven hundred and seventy-three subjects with bipolar disorder (BD), recruited across 14 centers, currently in the euthymic phase were cross-sectionally evaluated on Cognitive Complaints in Bipolar Disorder Rating Assessment (COBRA).
Results:
The mean total COBRA score was 9.79 (SD: 6.99), and 322 (41.7%) of the participants were found to have subjective cognitive complaints when the cut-off of >10 was used. Compared to those without cognitive complaints, those with cognitive complaints more often had depression as the first episode in their lifetime, had a higher prevalence of alcohol dependence, a higher number of depressive episodes (first five years of illness, lifetime, and per year of illness), a higher number of manic episodes in the first five years of illness, more often had depressive or indeterminate predominant polarity, lower prevalence of at least one-lifetime episode with psychotic symptoms, higher severity of residual symptoms, spent more time in the episodes in the lifetime, had poorer insight and higher disability.
Conclusion:
The present study suggests subjective complaints complaints are associated with more severe illness, higher levels of residual symptoms, poor insight, and higher disability. |
| format | Article |
| id | doaj-art-b94865b9f3cb48ab80c6ba8731e1c7b5 |
| institution | Kabale University |
| issn | 0019-5545 1998-3794 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Psychiatry |
| spelling | doaj-art-b94865b9f3cb48ab80c6ba8731e1c7b52025-01-20T11:10:31ZengWolters Kluwer Medknow PublicationsIndian Journal of Psychiatry0019-55451998-37942023-03-0165334535510.4103/indianjpsychiatry.indianjpsychiatry_367_22Subjective cognitive deficits and its correlates among patients with bipolar disorder: Findings from the bipolar disorder course and outcome study from India (BiD-CoIN study)Sandeep GroverAjit AvasthiRahul ChakravartyAmitava DanKaustav ChakrabortyRajarshi NeogiAvinash DesouzaOmkar NayakSamir PraharajVikas MenonRaman DeepManish BathlaAlka A. SubramanyamNaresh NebhinaniProsenjit GhoshBhavesh LakdawalaRanjan BhattacharyaAim: This study aimed to evaluate the prevalence of subjective cognitive complaints and their association with clinical variables, insight, and disability. Methodology: Seven hundred and seventy-three subjects with bipolar disorder (BD), recruited across 14 centers, currently in the euthymic phase were cross-sectionally evaluated on Cognitive Complaints in Bipolar Disorder Rating Assessment (COBRA). Results: The mean total COBRA score was 9.79 (SD: 6.99), and 322 (41.7%) of the participants were found to have subjective cognitive complaints when the cut-off of >10 was used. Compared to those without cognitive complaints, those with cognitive complaints more often had depression as the first episode in their lifetime, had a higher prevalence of alcohol dependence, a higher number of depressive episodes (first five years of illness, lifetime, and per year of illness), a higher number of manic episodes in the first five years of illness, more often had depressive or indeterminate predominant polarity, lower prevalence of at least one-lifetime episode with psychotic symptoms, higher severity of residual symptoms, spent more time in the episodes in the lifetime, had poorer insight and higher disability. Conclusion: The present study suggests subjective complaints complaints are associated with more severe illness, higher levels of residual symptoms, poor insight, and higher disability.https://journals.lww.com/10.4103/indianjpsychiatry.indianjpsychiatry_367_22bipolar disordercognitive complaintsdisabilityinsight |
| spellingShingle | Sandeep Grover Ajit Avasthi Rahul Chakravarty Amitava Dan Kaustav Chakraborty Rajarshi Neogi Avinash Desouza Omkar Nayak Samir Praharaj Vikas Menon Raman Deep Manish Bathla Alka A. Subramanyam Naresh Nebhinani Prosenjit Ghosh Bhavesh Lakdawala Ranjan Bhattacharya Subjective cognitive deficits and its correlates among patients with bipolar disorder: Findings from the bipolar disorder course and outcome study from India (BiD-CoIN study) Indian Journal of Psychiatry bipolar disorder cognitive complaints disability insight |
| title | Subjective cognitive deficits and its correlates among patients with bipolar disorder: Findings from the bipolar disorder course and outcome study from India (BiD-CoIN study) |
| title_full | Subjective cognitive deficits and its correlates among patients with bipolar disorder: Findings from the bipolar disorder course and outcome study from India (BiD-CoIN study) |
| title_fullStr | Subjective cognitive deficits and its correlates among patients with bipolar disorder: Findings from the bipolar disorder course and outcome study from India (BiD-CoIN study) |
| title_full_unstemmed | Subjective cognitive deficits and its correlates among patients with bipolar disorder: Findings from the bipolar disorder course and outcome study from India (BiD-CoIN study) |
| title_short | Subjective cognitive deficits and its correlates among patients with bipolar disorder: Findings from the bipolar disorder course and outcome study from India (BiD-CoIN study) |
| title_sort | subjective cognitive deficits and its correlates among patients with bipolar disorder findings from the bipolar disorder course and outcome study from india bid coin study |
| topic | bipolar disorder cognitive complaints disability insight |
| url | https://journals.lww.com/10.4103/indianjpsychiatry.indianjpsychiatry_367_22 |
| work_keys_str_mv | AT sandeepgrover subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT ajitavasthi subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT rahulchakravarty subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT amitavadan subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT kaustavchakraborty subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT rajarshineogi subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT avinashdesouza subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT omkarnayak subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT samirpraharaj subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT vikasmenon subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT ramandeep subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT manishbathla subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT alkaasubramanyam subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT nareshnebhinani subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT prosenjitghosh subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT bhaveshlakdawala subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy AT ranjanbhattacharya subjectivecognitivedeficitsanditscorrelatesamongpatientswithbipolardisorderfindingsfromthebipolardisordercourseandoutcomestudyfromindiabidcoinstudy |