Research Progress on Genome-Scale Metabolic Models of Lactic Acid Bacteria and Their Application in the Food System
Lactic acid bacteria (LAB) play a crucial role in improving the flavor and enhancing the nutritional value food, which have found wide application in the field of food fermentation. Genome-scale metabolic models (GSMMs) serve as essential tools for studying microbial metabolism, which simulate the m...
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| Format: | Article |
| Language: | English |
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China Food Publishing Company
2024-12-01
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| Series: | Shipin Kexue |
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| Online Access: | https://www.spkx.net.cn/fileup/1002-6630/PDF/2024-45-24-038.pdf |
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| author | LIU Zihao, NI Haojie, LI Wenlu, WANG Fengzhong, WANG Yanbo, ZENG Hong |
| author_facet | LIU Zihao, NI Haojie, LI Wenlu, WANG Fengzhong, WANG Yanbo, ZENG Hong |
| author_sort | LIU Zihao, NI Haojie, LI Wenlu, WANG Fengzhong, WANG Yanbo, ZENG Hong |
| collection | DOAJ |
| description | Lactic acid bacteria (LAB) play a crucial role in improving the flavor and enhancing the nutritional value food, which have found wide application in the field of food fermentation. Genome-scale metabolic models (GSMMs) serve as essential tools for studying microbial metabolism, which simulate the metabolic networks of microorganisms and accurately describe the genotype-phenotype relationships. Several GSMMs have already been successfully applied to the metabolic regulation of LAB. This article systematically summarizes LAB GSMMs constructed over the past two decades, emphasizing their application in food systems. Moreover, it analyzes the primary challenges and limitations of the GSMMs and gives an outlook on future directions in by combining emerging technologies and innovative ideas. The final goal is to provide valuable insights for the effective and precise application of LAB GSMMs to the intelligent design of microbial communities in the food industry. |
| format | Article |
| id | doaj-art-b94825e2ebd34e0ebd2b30a83ded0830 |
| institution | Kabale University |
| issn | 1002-6630 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | China Food Publishing Company |
| record_format | Article |
| series | Shipin Kexue |
| spelling | doaj-art-b94825e2ebd34e0ebd2b30a83ded08302025-02-05T09:08:02ZengChina Food Publishing CompanyShipin Kexue1002-66302024-12-01452434835610.7506/spkx1002-6630-20240614-093Research Progress on Genome-Scale Metabolic Models of Lactic Acid Bacteria and Their Application in the Food SystemLIU Zihao, NI Haojie, LI Wenlu, WANG Fengzhong, WANG Yanbo, ZENG Hong0(1. School of Food and Health, Beijing Technology and Business University, Beijing 100048, China; 2. Key Laboratory of Agro-products Quality &Safety in Harvest, Storage, Transportation, Management and Control, Ministry of Agriculture and Rural Affairs, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China)Lactic acid bacteria (LAB) play a crucial role in improving the flavor and enhancing the nutritional value food, which have found wide application in the field of food fermentation. Genome-scale metabolic models (GSMMs) serve as essential tools for studying microbial metabolism, which simulate the metabolic networks of microorganisms and accurately describe the genotype-phenotype relationships. Several GSMMs have already been successfully applied to the metabolic regulation of LAB. This article systematically summarizes LAB GSMMs constructed over the past two decades, emphasizing their application in food systems. Moreover, it analyzes the primary challenges and limitations of the GSMMs and gives an outlook on future directions in by combining emerging technologies and innovative ideas. The final goal is to provide valuable insights for the effective and precise application of LAB GSMMs to the intelligent design of microbial communities in the food industry.https://www.spkx.net.cn/fileup/1002-6630/PDF/2024-45-24-038.pdflactic acid bacteria; genome-scale metabolic model; metabolic simulation; food industry |
| spellingShingle | LIU Zihao, NI Haojie, LI Wenlu, WANG Fengzhong, WANG Yanbo, ZENG Hong Research Progress on Genome-Scale Metabolic Models of Lactic Acid Bacteria and Their Application in the Food System Shipin Kexue lactic acid bacteria; genome-scale metabolic model; metabolic simulation; food industry |
| title | Research Progress on Genome-Scale Metabolic Models of Lactic Acid Bacteria and Their Application in the Food System |
| title_full | Research Progress on Genome-Scale Metabolic Models of Lactic Acid Bacteria and Their Application in the Food System |
| title_fullStr | Research Progress on Genome-Scale Metabolic Models of Lactic Acid Bacteria and Their Application in the Food System |
| title_full_unstemmed | Research Progress on Genome-Scale Metabolic Models of Lactic Acid Bacteria and Their Application in the Food System |
| title_short | Research Progress on Genome-Scale Metabolic Models of Lactic Acid Bacteria and Their Application in the Food System |
| title_sort | research progress on genome scale metabolic models of lactic acid bacteria and their application in the food system |
| topic | lactic acid bacteria; genome-scale metabolic model; metabolic simulation; food industry |
| url | https://www.spkx.net.cn/fileup/1002-6630/PDF/2024-45-24-038.pdf |
| work_keys_str_mv | AT liuzihaonihaojieliwenluwangfengzhongwangyanbozenghong researchprogressongenomescalemetabolicmodelsoflacticacidbacteriaandtheirapplicationinthefoodsystem |