Effects of the combination of melatonin and N-acetylcysteine on the inflammatory response in a rat model of cerebral ischemia

Effects of the combination of melatonin and N-acetylcysteine on the inflammatory response in a rat model of cerebral ischemia

Stroke is the second leading cause of death and long-term damage globally. Inflammation is a significant factor in the onset of ischemic stroke. This study investigated the simultaneous administration of melatonin and N-acetylcysteine (NAC) on inflammation in rat cerebral ischemia. First, 30 male Wi...

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Bibliographic Details
Main Authors: Pouria Soleimani, Saied Nekoonam, Fariba Zafari, Fatemeh Sabbaghziarani
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:IBRO Neuroscience Reports
Subjects:
Cerebral ischemia
Inflammation
Melatonin
N-acetylcysteine (NAC)
Cytokines
Inflammasomes
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242125000879
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