A Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold Nanoparticles

Bisphenol A (BPA) is a commonly synthetic chemical mainly used in producing plastic items. It is an endocrine-disrupting compound that causes irreversible health and environmental damage. Developing a simple method for BPA effective quantitative monitoring is emergently necessary. Herein, a novel el...

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Main Authors: Fatma Rejab, Nour Elhouda Dardouri, Ahlem Rouis, Mosaab Echabaane, Habib Nasri, Boris Lakard, Hamdi Ben Halima, Nicole Jaffrezic-Renault
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Micromachines
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Online Access:https://www.mdpi.com/2072-666X/15/12/1508
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author Fatma Rejab
Nour Elhouda Dardouri
Ahlem Rouis
Mosaab Echabaane
Habib Nasri
Boris Lakard
Hamdi Ben Halima
Nicole Jaffrezic-Renault
author_facet Fatma Rejab
Nour Elhouda Dardouri
Ahlem Rouis
Mosaab Echabaane
Habib Nasri
Boris Lakard
Hamdi Ben Halima
Nicole Jaffrezic-Renault
author_sort Fatma Rejab
collection DOAJ
description Bisphenol A (BPA) is a commonly synthetic chemical mainly used in producing plastic items. It is an endocrine-disrupting compound that causes irreversible health and environmental damage. Developing a simple method for BPA effective quantitative monitoring is emergently necessary. Herein, a novel electrochemical sensor for BPA detection based on [(5,10,15,20-tetrakis(p-bromophenyl) porphyrinato] cadmium (II) [(CdTBrPP)] and gold nanoparticle (AuNPs)-modified screen-printed carbon electrode (SPCE) was elaborated. CdTBrPP was synthesized and then characterized with Ultraviolet–Visible Spectroscopy (UV/vis), Infrared Spectroscopy (IR), and Proton Nuclear Magnetic Resonance Spectroscopy (<sup>1</sup>H NMR) to confirm its successful synthesis. After drop-coating AuNPs and CdTBrPP on the SPCE, the sensor performance was evaluated using square wave voltammetry (SWV), a linear response in a concentration range from 10<sup>−11</sup> M to 10<sup>−2</sup> M, with a low detection limit (LOD) of 9.5 pM. The CdTBrPP/AuNPs/SPCE sensor demonstrates a high selectivity and reproducibility, making it a promising candidate for developing a low-cost water-monitoring system for detecting BPA. Additionally, the proposed sensor effectively detected BPA in both tap and mineral water samples.
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spelling doaj-art-b93a286968e348cf86007b61ebc6d46d2025-08-20T02:57:27ZengMDPI AGMicromachines2072-666X2024-12-011512150810.3390/mi15121508A Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold NanoparticlesFatma Rejab0Nour Elhouda Dardouri1Ahlem Rouis2Mosaab Echabaane3Habib Nasri4Boris Lakard5Hamdi Ben Halima6Nicole Jaffrezic-Renault7Faculty of Sciences of Monastir, Laboratory of Advanced Materials and Interfaces (LIMA), University of Monastir, Avenue of the Environment, Monastir 5000, TunisiaFaculty of Sciences of Monastir, Laboratory of Physical Chemistry of Materials, University of Monastir, Avenue of Environment, Monastir 5019, TunisiaFaculty of Sciences of Monastir, Laboratory of Advanced Materials and Interfaces (LIMA), University of Monastir, Avenue of the Environment, Monastir 5000, TunisiaCRMN, Centre for Research on Microelectronics and Nanotechnology of Sousse, NANOMISENE, LR16CRMN01, Sousse 4054, TunisiaFaculty of Sciences of Monastir, Laboratory of Physical Chemistry of Materials, University of Monastir, Avenue of Environment, Monastir 5019, TunisiaInstitute of UTINAM, UMR-CNRS 6213, University of Franche-Comté, 16 Gray Road, 25030 Besançon, FranceInstitute of UTINAM, UMR-CNRS 6213, University of Franche-Comté, 16 Gray Road, 25030 Besançon, FranceInstitute of UTINAM, UMR-CNRS 6213, University of Franche-Comté, 16 Gray Road, 25030 Besançon, FranceBisphenol A (BPA) is a commonly synthetic chemical mainly used in producing plastic items. It is an endocrine-disrupting compound that causes irreversible health and environmental damage. Developing a simple method for BPA effective quantitative monitoring is emergently necessary. Herein, a novel electrochemical sensor for BPA detection based on [(5,10,15,20-tetrakis(p-bromophenyl) porphyrinato] cadmium (II) [(CdTBrPP)] and gold nanoparticle (AuNPs)-modified screen-printed carbon electrode (SPCE) was elaborated. CdTBrPP was synthesized and then characterized with Ultraviolet–Visible Spectroscopy (UV/vis), Infrared Spectroscopy (IR), and Proton Nuclear Magnetic Resonance Spectroscopy (<sup>1</sup>H NMR) to confirm its successful synthesis. After drop-coating AuNPs and CdTBrPP on the SPCE, the sensor performance was evaluated using square wave voltammetry (SWV), a linear response in a concentration range from 10<sup>−11</sup> M to 10<sup>−2</sup> M, with a low detection limit (LOD) of 9.5 pM. The CdTBrPP/AuNPs/SPCE sensor demonstrates a high selectivity and reproducibility, making it a promising candidate for developing a low-cost water-monitoring system for detecting BPA. Additionally, the proposed sensor effectively detected BPA in both tap and mineral water samples.https://www.mdpi.com/2072-666X/15/12/1508electrochemical sensorcadmium metalloporphyrinsquare wave voltammetrybisphenol A
spellingShingle Fatma Rejab
Nour Elhouda Dardouri
Ahlem Rouis
Mosaab Echabaane
Habib Nasri
Boris Lakard
Hamdi Ben Halima
Nicole Jaffrezic-Renault
A Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold Nanoparticles
Micromachines
electrochemical sensor
cadmium metalloporphyrin
square wave voltammetry
bisphenol A
title A Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold Nanoparticles
title_full A Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold Nanoparticles
title_fullStr A Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold Nanoparticles
title_full_unstemmed A Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold Nanoparticles
title_short A Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold Nanoparticles
title_sort selective electrochemical sensor for bisphenol a detection based on cadmium ii bromophenyl porphyrin and gold nanoparticles
topic electrochemical sensor
cadmium metalloporphyrin
square wave voltammetry
bisphenol A
url https://www.mdpi.com/2072-666X/15/12/1508
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