Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno-Histochemistry and Tv Image Cytometry

Backgound: Epithelial cell proliferation activity has been reported both to be unaltered and increased in Helicobacter pylori (H. pylori) associated chronic gastritis. The proliferation rate decreased following H. pylori eradication, but results are controversial whether this change is dependent on...

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Main Authors: Erika Szaleczky, László Prónai, Béla Molnár, Lajos Berczi, János Fehér, Zsolt Tulassay
Format: Article
Language:English
Published: Wiley 2000-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2000/830906
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author Erika Szaleczky
László Prónai
Béla Molnár
Lajos Berczi
János Fehér
Zsolt Tulassay
author_facet Erika Szaleczky
László Prónai
Béla Molnár
Lajos Berczi
János Fehér
Zsolt Tulassay
author_sort Erika Szaleczky
collection DOAJ
description Backgound: Epithelial cell proliferation activity has been reported both to be unaltered and increased in Helicobacter pylori (H. pylori) associated chronic gastritis. The proliferation rate decreased following H. pylori eradication, but results are controversial whether this change is dependent on the success of eradication. We compared the cell proliferation activity of H. pylori positive and negative gastric epithelial biopsies in chronic gastritis with and without intestinal metaplasia (IM) and gastric cancer by the expression of proliferation cell nuclear antigen (PCNA) and Tv image cytometry, and assessed the effect of H. pylori eradication on the cell proliferation rate in the gastric epithelium.
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institution Kabale University
issn 0921-8912
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publishDate 2000-01-01
publisher Wiley
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series Analytical Cellular Pathology
spelling doaj-art-b922346048454d229ae76905c724db352025-02-03T01:06:56ZengWileyAnalytical Cellular Pathology0921-89121878-36512000-01-01202-313113910.1155/2000/830906Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno-Histochemistry and Tv Image CytometryErika Szaleczky0László Prónai1Béla Molnár2Lajos Berczi3János Fehér4Zsolt Tulassay52nd Department of Internal Medicine, Clinical Gastroenterology and Endocrinology Unit, Semmelweis University of Medicine, Budapest, Hungary2nd Department of Internal Medicine, Clinical Gastroenterology and Endocrinology Unit, Semmelweis University of Medicine, Budapest, Hungary2nd Department of Internal Medicine, Clinical Gastroenterology and Endocrinology Unit, Semmelweis University of Medicine, Budapest, Hungary1st Institute of Pathology and Experimental Cancer Research, Semmelweis University of Medicine, Budapest, Hungary2nd Department of Internal Medicine, Clinical Gastroenterology and Endocrinology Unit, Semmelweis University of Medicine, Budapest, Hungary2nd Department of Internal Medicine, Clinical Gastroenterology and Endocrinology Unit, Semmelweis University of Medicine, Budapest, HungaryBackgound: Epithelial cell proliferation activity has been reported both to be unaltered and increased in Helicobacter pylori (H. pylori) associated chronic gastritis. The proliferation rate decreased following H. pylori eradication, but results are controversial whether this change is dependent on the success of eradication. We compared the cell proliferation activity of H. pylori positive and negative gastric epithelial biopsies in chronic gastritis with and without intestinal metaplasia (IM) and gastric cancer by the expression of proliferation cell nuclear antigen (PCNA) and Tv image cytometry, and assessed the effect of H. pylori eradication on the cell proliferation rate in the gastric epithelium.http://dx.doi.org/10.1155/2000/830906
spellingShingle Erika Szaleczky
László Prónai
Béla Molnár
Lajos Berczi
János Fehér
Zsolt Tulassay
Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno-Histochemistry and Tv Image Cytometry
Analytical Cellular Pathology
title Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno-Histochemistry and Tv Image Cytometry
title_full Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno-Histochemistry and Tv Image Cytometry
title_fullStr Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno-Histochemistry and Tv Image Cytometry
title_full_unstemmed Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno-Histochemistry and Tv Image Cytometry
title_short Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno-Histochemistry and Tv Image Cytometry
title_sort increased cell proliferation in chronic helicobacter pylori positive gastritis and gastric carcinoma correlation between immuno histochemistry and tv image cytometry
url http://dx.doi.org/10.1155/2000/830906
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