Anti-Yo Associated Paraneoplastic Cerebellar Degeneration in a Man with Large Cell Cancer of the Lung
Purkinje cell cytoplasmic antibody type 1 (PCA-1), or anti-Yo, is the most frequently detected autoantibody in paraneoplastic cerebellar degeneration (PCD). The vast majority of cases of anti-Yo PCD, however, occur in females over 60 years old and are associated with gynecologic tumors. Only 10 case...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/725936 |
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| _version_ | 1849686144129695744 |
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| author | Linda Hasadsri James Lee Bonnie H. Wang Lalitha Yekkirala Mingtao Wang |
| author_facet | Linda Hasadsri James Lee Bonnie H. Wang Lalitha Yekkirala Mingtao Wang |
| author_sort | Linda Hasadsri |
| collection | DOAJ |
| description | Purkinje cell cytoplasmic antibody type 1 (PCA-1), or anti-Yo, is the most frequently detected autoantibody in paraneoplastic cerebellar degeneration (PCD). The vast majority of cases of anti-Yo PCD, however, occur in females over 60 years old and are associated with gynecologic tumors. Only 10 cases have been reported in males, and only 2 were associated with cancer of the lung. Here we describe the youngest known case of PCA-1 positive PCD in a male, whose lung tumor was undetectable even on FDG-PET. |
| format | Article |
| id | doaj-art-b91f3a1dee524014a8dd997e31ca26d4 |
| institution | DOAJ |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-b91f3a1dee524014a8dd997e31ca26d42025-08-20T03:22:49ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/725936725936Anti-Yo Associated Paraneoplastic Cerebellar Degeneration in a Man with Large Cell Cancer of the LungLinda Hasadsri0James Lee1Bonnie H. Wang2Lalitha Yekkirala3Mingtao Wang4Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USADepartment of Internal Medicine, University of Illinois Urbana-Champaign, 611 W. Park Street, Urbana, IL 61801, USADepartment of Internal Medicine, University of Illinois Urbana-Champaign, 611 W. Park Street, Urbana, IL 61801, USADepartment of Internal Medicine, University of Illinois Urbana-Champaign, 611 W. Park Street, Urbana, IL 61801, USADepartment of Neurology, University of Illinois Urbana-Champaign, 611 W. Park Street, Urbana, IL 61801, USAPurkinje cell cytoplasmic antibody type 1 (PCA-1), or anti-Yo, is the most frequently detected autoantibody in paraneoplastic cerebellar degeneration (PCD). The vast majority of cases of anti-Yo PCD, however, occur in females over 60 years old and are associated with gynecologic tumors. Only 10 cases have been reported in males, and only 2 were associated with cancer of the lung. Here we describe the youngest known case of PCA-1 positive PCD in a male, whose lung tumor was undetectable even on FDG-PET.http://dx.doi.org/10.1155/2013/725936 |
| spellingShingle | Linda Hasadsri James Lee Bonnie H. Wang Lalitha Yekkirala Mingtao Wang Anti-Yo Associated Paraneoplastic Cerebellar Degeneration in a Man with Large Cell Cancer of the Lung Case Reports in Neurological Medicine |
| title | Anti-Yo Associated Paraneoplastic Cerebellar Degeneration in a Man with Large Cell Cancer of the Lung |
| title_full | Anti-Yo Associated Paraneoplastic Cerebellar Degeneration in a Man with Large Cell Cancer of the Lung |
| title_fullStr | Anti-Yo Associated Paraneoplastic Cerebellar Degeneration in a Man with Large Cell Cancer of the Lung |
| title_full_unstemmed | Anti-Yo Associated Paraneoplastic Cerebellar Degeneration in a Man with Large Cell Cancer of the Lung |
| title_short | Anti-Yo Associated Paraneoplastic Cerebellar Degeneration in a Man with Large Cell Cancer of the Lung |
| title_sort | anti yo associated paraneoplastic cerebellar degeneration in a man with large cell cancer of the lung |
| url | http://dx.doi.org/10.1155/2013/725936 |
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