Texture Analysis of CT Images in Differential Diagnosis of Non-Small Cell Lung Cancer

Background. In current clinical practice, the information contained in computed tomography (CT) images of lung cancer is not used to its full extent – only a few semantic characteristics (e.g. size, contours, nature of contrast agent accumulation, etc.). Today, researchers are attempting to transfor...

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Main Authors: V. O. Vorobeva, I. E. Tyurin
Format: Article
Language:English
Published: Luchevaya Diagnostika, LLC 2025-07-01
Series:Вестник рентгенологии и радиологии
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Online Access:https://www.russianradiology.ru/jour/article/view/938
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author V. O. Vorobeva
I. E. Tyurin
author_facet V. O. Vorobeva
I. E. Tyurin
author_sort V. O. Vorobeva
collection DOAJ
description Background. In current clinical practice, the information contained in computed tomography (CT) images of lung cancer is not used to its full extent – only a few semantic characteristics (e.g. size, contours, nature of contrast agent accumulation, etc.). Today, researchers are attempting to transform CT image data into quantitative indicators describing the shape and texture of lung cancer, as well as to link these indicators with clinical data. This approach is called “radiomics” and is a developing field in medicine.Objective: to analyze publications on differential diagnosis of non-small cell lung cancer (NSCLC) using texture analysis as well as to assess the possibilities and prospects of this method in increasing information content of CT studies.Material and methods. The literature review presents data obtained from available sources in PubMed, ScienceDirect and Google Scholar databases, published up to and including the end of 2024, found using the key words and phrases in Russian and English languages: “NSCLC”, “lung adenocarcinoma”, “squamous cell lung cancer”, “computed tomography”, “radiomics”, “texture analysis”, “differential diagnostics”.Results. The literature review describes the methods of texture analysis at all stages. Based on the results of the studied scientific works, the authors conclude that the use of texture analysis allows non-invasively predicting the histological form of NSCLC with sensitivity 72–83%, specificity 67–92%, and accuracy 74–86%. Conclusion. The use of texture analysis, according to published studies, is a promising method for differential diagnosis of histological forms of NSCLC (up to AUC ~0.7–0.9), however, the difference in methods and the lack of standardization of texture analysis require additional research.
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spelling doaj-art-b9192e3e3cc146bf8a0cc77f17978f5e2025-08-20T03:58:45ZengLuchevaya Diagnostika, LLCВестник рентгенологии и радиологии0042-46762619-04782025-07-01105633534310.20862/0042-4676-2024-105-6-335-343490Texture Analysis of CT Images in Differential Diagnosis of Non-Small Cell Lung CancerV. O. Vorobeva0I. E. Tyurin1Blokhin National Medical Research Center of OncologyBlokhin National Medical Research Center of Oncology; Russian Medical Academy of Continuous Professional EducationBackground. In current clinical practice, the information contained in computed tomography (CT) images of lung cancer is not used to its full extent – only a few semantic characteristics (e.g. size, contours, nature of contrast agent accumulation, etc.). Today, researchers are attempting to transform CT image data into quantitative indicators describing the shape and texture of lung cancer, as well as to link these indicators with clinical data. This approach is called “radiomics” and is a developing field in medicine.Objective: to analyze publications on differential diagnosis of non-small cell lung cancer (NSCLC) using texture analysis as well as to assess the possibilities and prospects of this method in increasing information content of CT studies.Material and methods. The literature review presents data obtained from available sources in PubMed, ScienceDirect and Google Scholar databases, published up to and including the end of 2024, found using the key words and phrases in Russian and English languages: “NSCLC”, “lung adenocarcinoma”, “squamous cell lung cancer”, “computed tomography”, “radiomics”, “texture analysis”, “differential diagnostics”.Results. The literature review describes the methods of texture analysis at all stages. Based on the results of the studied scientific works, the authors conclude that the use of texture analysis allows non-invasively predicting the histological form of NSCLC with sensitivity 72–83%, specificity 67–92%, and accuracy 74–86%. Conclusion. The use of texture analysis, according to published studies, is a promising method for differential diagnosis of histological forms of NSCLC (up to AUC ~0.7–0.9), however, the difference in methods and the lack of standardization of texture analysis require additional research.https://www.russianradiology.ru/jour/article/view/938computed tomographytexture analysisnon-small cell lung cancerreview
spellingShingle V. O. Vorobeva
I. E. Tyurin
Texture Analysis of CT Images in Differential Diagnosis of Non-Small Cell Lung Cancer
Вестник рентгенологии и радиологии
computed tomography
texture analysis
non-small cell lung cancer
review
title Texture Analysis of CT Images in Differential Diagnosis of Non-Small Cell Lung Cancer
title_full Texture Analysis of CT Images in Differential Diagnosis of Non-Small Cell Lung Cancer
title_fullStr Texture Analysis of CT Images in Differential Diagnosis of Non-Small Cell Lung Cancer
title_full_unstemmed Texture Analysis of CT Images in Differential Diagnosis of Non-Small Cell Lung Cancer
title_short Texture Analysis of CT Images in Differential Diagnosis of Non-Small Cell Lung Cancer
title_sort texture analysis of ct images in differential diagnosis of non small cell lung cancer
topic computed tomography
texture analysis
non-small cell lung cancer
review
url https://www.russianradiology.ru/jour/article/view/938
work_keys_str_mv AT vovorobeva textureanalysisofctimagesindifferentialdiagnosisofnonsmallcelllungcancer
AT ietyurin textureanalysisofctimagesindifferentialdiagnosisofnonsmallcelllungcancer