Diagnostic accuracy of urinary PENK methylation test for urothelial and other cancers: A prospective study

Diagnostic accuracy of urinary PENK methylation test for urothelial and other cancers: A prospective study

Abstract The methylated PENK gene is known to be highly expressed in the urine of patients with bladder cancer. Recent large-scale multicenter studies have confirmed the robust diagnostic performance of urinary PENK methylation, reporting high sensitivity and specificity for bladder cancer detection...

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Bibliographic Details
Main Authors: Sangmin Lee, Bumjin Lim, Jungyo Suh, Bumsik Hong, In Gab Jeong
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
DNA methylation
Hematuria
Tumor biomarkers
Urinary bladder neoplasms
Online Access:https://doi.org/10.1038/s41598-025-07173-5
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