The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children
A total of 8898 Chinese children (4580 boys and 4318 girls) aged 7–13 years in 6 cities of east China were recruited. Data on height, weight, waist circumference, blood pressure, serum lipid profiles, glucose, and insulin were collected. The overall prevalence of hypertension was 11.1%. Overweight a...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.4061/2011/987159 |
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| author | Haiquan Xu Xiaoqi Hu Qian Zhang Songming Du Hongyun Fang Ying Li Jun Ma Tingyu Li Lin Du Hongwei Guo Guifa Xu Ailing Liu |
| author_facet | Haiquan Xu Xiaoqi Hu Qian Zhang Songming Du Hongyun Fang Ying Li Jun Ma Tingyu Li Lin Du Hongwei Guo Guifa Xu Ailing Liu |
| author_sort | Haiquan Xu |
| collection | DOAJ |
| description | A total of 8898 Chinese children (4580 boys and 4318 girls) aged 7–13 years in 6 cities of east China were recruited. Data on height, weight, waist circumference, blood pressure, serum lipid profiles, glucose, and insulin were collected. The overall prevalence of hypertension was 11.1%. Overweight and obese children had a higher risk of developing hypertension than their counterparts (29.1%, 17.4%, and 7.8%, resp.) (P=0.0001). The means levels of triglycerides, glucose, insulin, and HOMA-IR (1.0 mmol/L, 4.5 mmol/L, 8.4 mU/mL and 1.7, resp.) among hypertensive children were all significantly higher than their normotensive counterparts (0.8 mmol/L, 4.5 mmol/L, 5.9 mU/mL, and 1.2, resp.) (P=0.0001). Compared with the healthy children, the risk (odds ratio, OR) of having hypertension among children with high triglycerides, hyperglycemia, and metabolic syndrome was 1.4 (95% confidence interval (CI): 1.0–2.0, P=0.0334), 1.5 (95% CI: 0.9–2.5, P=0.0890), and 2.8 (95%CI: 1.5–5.4, P=0.0014), respectively, after controlling for age, gender, BMI, income level, parents' education level and puberty. In conclusion, overweight and obese children have higher risk of having hypertension and children with dyslipidemia, hyperglycemia, and metabolic syndrome and higher HOMA-IR have higher risk of developing hypertension. |
| format | Article |
| id | doaj-art-b914dc0b69f74927b528cb06dba016ee |
| institution | DOAJ |
| issn | 2090-0392 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-b914dc0b69f74927b528cb06dba016ee2025-08-20T03:22:50ZengWileyInternational Journal of Hypertension2090-03922011-01-01201110.4061/2011/987159987159The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese ChildrenHaiquan Xu0Xiaoqi Hu1Qian Zhang2Songming Du3Hongyun Fang4Ying Li5Jun Ma6Tingyu Li7Lin Du8Hongwei Guo9Guifa Xu10Ailing Liu11National Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaNational Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaNational Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaNational Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaNational Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaHaerbin Medical University, Heilongjiang, Haerbin 150081, ChinaInstitute of Children and Adolescent Health, Peking University Health Science Center, Beijing 100191, ChinaChongqing Children’s Hospital, Chongqing 400014, ChinaGuangzhou Center for Disease Control and Prevention, Guangdong, Guangzhou 510515, ChinaSchool of Public Health, Fudan University, Shanghai 200032, ChinaDepartment of Public Health, Shandong University, Shandong, Jinan 250012, ChinaNational Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, ChinaA total of 8898 Chinese children (4580 boys and 4318 girls) aged 7–13 years in 6 cities of east China were recruited. Data on height, weight, waist circumference, blood pressure, serum lipid profiles, glucose, and insulin were collected. The overall prevalence of hypertension was 11.1%. Overweight and obese children had a higher risk of developing hypertension than their counterparts (29.1%, 17.4%, and 7.8%, resp.) (P=0.0001). The means levels of triglycerides, glucose, insulin, and HOMA-IR (1.0 mmol/L, 4.5 mmol/L, 8.4 mU/mL and 1.7, resp.) among hypertensive children were all significantly higher than their normotensive counterparts (0.8 mmol/L, 4.5 mmol/L, 5.9 mU/mL, and 1.2, resp.) (P=0.0001). Compared with the healthy children, the risk (odds ratio, OR) of having hypertension among children with high triglycerides, hyperglycemia, and metabolic syndrome was 1.4 (95% confidence interval (CI): 1.0–2.0, P=0.0334), 1.5 (95% CI: 0.9–2.5, P=0.0890), and 2.8 (95%CI: 1.5–5.4, P=0.0014), respectively, after controlling for age, gender, BMI, income level, parents' education level and puberty. In conclusion, overweight and obese children have higher risk of having hypertension and children with dyslipidemia, hyperglycemia, and metabolic syndrome and higher HOMA-IR have higher risk of developing hypertension.http://dx.doi.org/10.4061/2011/987159 |
| spellingShingle | Haiquan Xu Xiaoqi Hu Qian Zhang Songming Du Hongyun Fang Ying Li Jun Ma Tingyu Li Lin Du Hongwei Guo Guifa Xu Ailing Liu The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children International Journal of Hypertension |
| title | The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children |
| title_full | The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children |
| title_fullStr | The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children |
| title_full_unstemmed | The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children |
| title_short | The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children |
| title_sort | association of hypertension with obesity and metabolic abnormalities among chinese children |
| url | http://dx.doi.org/10.4061/2011/987159 |
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