Zika virus differentially infects human neural progenitor cells according to their state of differentiation and dysregulates neurogenesis through the Notch pathway

Zika virus differentially infects human neural progenitor cells according to their state of differentiation and dysregulates neurogenesis through the Notch pathway

Zika virus (ZIKV) is a mosquito-borne Flavivirus that causes Zika disease with particular neurological complications, including Guillain-Barré Syndrome and congenital microcephaly. Although ZIKV has been shown to directly infect human neural progenitor cells (hNPCs), thereby decreasing their viabil...

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Bibliographic Details
Main Authors: Pauline Ferraris, Marielle Cochet, Rodolphe Hamel, Ivan Gladwyn-Ng, Christian Alfano, Fodé Diop, Déborah Garcia, Loïc Talignani, Claudia N. Montero-Menei, Antoine Nougairède, Hans Yssel, Laurent Nguyen, Muriel Coulpier, Dorothée Missé
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
Subjects:
Zika
arbovirus
human neural progenitor
Notch
neurogenesis
flavivirus
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2019.1637283
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