Metabolomic and proteomic profiling of a burn-hemorrhagic shock swine model reveals a metabolomic signature associated with fatal outcomes

Metabolomic and proteomic profiling of a burn-hemorrhagic shock swine model reveals a metabolomic signature associated with fatal outcomes

Abstract Background Burn-hemorrhagic shock combined injury, a severe condition causing complex stress responses and metabolic disturbances that significantly affect clinical outcomes in both military and civilian settings, was modeled in swine to investigate the associated metabolomic and proteomic...

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Main Authors: Bin Wei, Jinguang Zheng, Jiake Chai, Jianxiang Huang, Hongjie Duan, Shaofang Han, Xiaolin Yang, Wenjia Zhang, Fangchao Hu, Yirui Qu, Xiangyu Liu, Tian Liu, Yushou Wu, Yunfei Chi
Format: Article
Language:English
Published: BMC 2025-01-01
Series:European Journal of Medical Research
Subjects:
Burn-hemorrhagic shock combined injury
Organic acids
Amino acids
Matrix and RBC-related proteins
Online Access:https://doi.org/10.1186/s40001-024-02245-0
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