Eosinophilic Esophagitis in Children
Eosinophilic esophagitis is a chronic, immune/antigen-mediated esophageal inflammatory disease characterized by a pronounced eosinophilic infiltration of its mucous membrane. The occurrence of eosinophilia and damage of the esophageal mucous membrane is caused by exposure to food and aeroallergens,...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2016-08-01
|
| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/1635 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849411663488352256 |
|---|---|
| author | Tatyana N. Budkina Igor S. Sadikov Svetlana G. Makarova Maksim M. Lokhmatov Aleksandra V. Surzhik Oksana A. Ereshko |
| author_facet | Tatyana N. Budkina Igor S. Sadikov Svetlana G. Makarova Maksim M. Lokhmatov Aleksandra V. Surzhik Oksana A. Ereshko |
| author_sort | Tatyana N. Budkina |
| collection | DOAJ |
| description | Eosinophilic esophagitis is a chronic, immune/antigen-mediated esophageal inflammatory disease characterized by a pronounced eosinophilic infiltration of its mucous membrane. The occurrence of eosinophilia and damage of the esophageal mucous membrane is caused by exposure to food and aeroallergens, by genetic predisposition, and by activation of immune responses mediated by T-helper 2. In pediatric, eosinophilic esophagitis is most common in preschool and school-aged children with a burdened allergic history. Clinically, eosinophilic esophagitis is manifested by epigastric pain, symptoms similar to gastroesophageal reflux disease, and dysphagia. Diagnosis of eosinophilic esophagitis is based on clinical symptoms, characteristic endoscopic and morphological changes in the esophageal mucous membrane. The article presents algorithms for examination, dynamic observation and treatment of children with eosinophilic esophagitis, developed by The European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN), describes the recommendations for biopsy of the esophageal mucous membrane when eosinophilic esophagitis is suspected. Treatment of children with eosinophilic esophagitis is based on the following approaches: trial treatment by proton pump inhibitors for 2 months, diet correction and, if ineffective, the use of topical corticosteroids. |
| format | Article |
| id | doaj-art-b8ffa51a51934dcaa3ba077f643fdb5b |
| institution | Kabale University |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2016-08-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-b8ffa51a51934dcaa3ba077f643fdb5b2025-08-20T03:34:42Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352016-08-0115323924910.15690/vsp.v15i3.15601597Eosinophilic Esophagitis in ChildrenTatyana N. Budkina0Igor S. Sadikov1Svetlana G. Makarova2Maksim M. Lokhmatov3Aleksandra V. Surzhik4Oksana A. Ereshko5Scientific Center of Children’s Health, Moscow, Russian FederationScientific Center of Children’s Health, Moscow, Russian FederationScientific Center of Children’s Health, Moscow, Russian Federation I.M. Sechenov First Moscow State Medical University, Moscow, Russian FederationScientific Center of Children’s Health, Moscow, Russian Federation I.M. Sechenov First Moscow State Medical University, Moscow, Russian FederationNutricia LLC, Moscow, Russian FederationScientific Center of Children’s Health, Moscow, Russian Federation I.M. Sechenov First Moscow State Medical University, Moscow, Russian FederationEosinophilic esophagitis is a chronic, immune/antigen-mediated esophageal inflammatory disease characterized by a pronounced eosinophilic infiltration of its mucous membrane. The occurrence of eosinophilia and damage of the esophageal mucous membrane is caused by exposure to food and aeroallergens, by genetic predisposition, and by activation of immune responses mediated by T-helper 2. In pediatric, eosinophilic esophagitis is most common in preschool and school-aged children with a burdened allergic history. Clinically, eosinophilic esophagitis is manifested by epigastric pain, symptoms similar to gastroesophageal reflux disease, and dysphagia. Diagnosis of eosinophilic esophagitis is based on clinical symptoms, characteristic endoscopic and morphological changes in the esophageal mucous membrane. The article presents algorithms for examination, dynamic observation and treatment of children with eosinophilic esophagitis, developed by The European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN), describes the recommendations for biopsy of the esophageal mucous membrane when eosinophilic esophagitis is suspected. Treatment of children with eosinophilic esophagitis is based on the following approaches: trial treatment by proton pump inhibitors for 2 months, diet correction and, if ineffective, the use of topical corticosteroids.https://vsp.spr-journal.ru/jour/article/view/1635childreneosinophilic esophagitisesophagogastroduodenoscopydiet correctiontreatment. |
| spellingShingle | Tatyana N. Budkina Igor S. Sadikov Svetlana G. Makarova Maksim M. Lokhmatov Aleksandra V. Surzhik Oksana A. Ereshko Eosinophilic Esophagitis in Children Вопросы современной педиатрии children eosinophilic esophagitis esophagogastroduodenoscopy diet correction treatment. |
| title | Eosinophilic Esophagitis in Children |
| title_full | Eosinophilic Esophagitis in Children |
| title_fullStr | Eosinophilic Esophagitis in Children |
| title_full_unstemmed | Eosinophilic Esophagitis in Children |
| title_short | Eosinophilic Esophagitis in Children |
| title_sort | eosinophilic esophagitis in children |
| topic | children eosinophilic esophagitis esophagogastroduodenoscopy diet correction treatment. |
| url | https://vsp.spr-journal.ru/jour/article/view/1635 |
| work_keys_str_mv | AT tatyananbudkina eosinophilicesophagitisinchildren AT igorssadikov eosinophilicesophagitisinchildren AT svetlanagmakarova eosinophilicesophagitisinchildren AT maksimmlokhmatov eosinophilicesophagitisinchildren AT aleksandravsurzhik eosinophilicesophagitisinchildren AT oksanaaereshko eosinophilicesophagitisinchildren |