Association of clonal hematopoiesis of indeterminate potential with cardiometabolic multimorbidity progression and mortality: a prospective study of UK Biobank

Abstract Background Clonal hematopoiesis of indeterminate potential (CHIP) is defined as the aging-related clonal expansion of preleukemic mutations in hematopoietic stem cells. While CHIP has been studied in cardiometabolic diseases (CMDs), its role in the long-term progression from the absence of...

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Bibliographic Details
Main Authors: Chenzhe Zuo, Dihan Fu, Yuanfeng Huang, Jinchen Li, Shujun Yang, Xunjie Cheng, Guogang Zhang, Tianqi Ma, Qunyong Peng, Yu Tan
Format: Article
Language:English
Published: BMC 2025-05-01
Series:European Journal of Medical Research
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Online Access:https://doi.org/10.1186/s40001-025-02639-8
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