Visual Acuity, Full-field Stimulus Thresholds, and Electroretinography for 4 Years in The Rate of Progression of USH2A-related Retinal Degeneration (RUSH2A) Study

Visual Acuity, Full-field Stimulus Thresholds, and Electroretinography for 4 Years in The Rate of Progression of USH2A-related Retinal Degeneration (RUSH2A) Study

Purpose: To describe progression of best-corrected visual acuity (BCVA), full-field stimulus thresholds (FST), and electroretinography (ERG) over 4 years in the USH2A-related Retinal Degeneration study and to assess their suitability as clinical trial endpoints. Design: Prospective natural history s...

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Main Authors: David G. Birch, PhD, Peiyao Cheng, PhD, Maureen G. Maguire, PhD, Jacque L. Duncan, MD, Allison R. Ayala, MS, Janet K. Cheetham, PharmD, Nicole R. Doucet, MPH, Todd A. Durham, PhD, Abigail T. Fahim, MD, PhD, Frederick L. Ferris, III, MD, Rachel M. Huckfeldt, MD, PhD, Michele Melia, ScM, Michel Michaelides, MD (Res), Mark E. Pennesi, MD, PhD, José-Alain Sahel, MD, Katarina Stingl, MD, Ajoy Vincent, MBBS, MS, Christina Y. Weng, MD, MBA
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Ophthalmology Science
Subjects:
Electroretinography (ERG)
Full-field stimulus thresholds (FST)
Best-corrected visual acuity (BCVA)
Retinal degeneration
USH2A
Online Access:http://www.sciencedirect.com/science/article/pii/S2666914524001842
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