Investigation of Pharmaceuticals in Sakarya Sewage Wastewater

Active substances of drugs can cause various adverse effects by accumulating in the ecosystem. Many medications are resistant to biodegradation, given the recipient media in conventional wastewater treatment plants, and are thus released into the environment after only partial purification or no pur...

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Main Authors: Nihan Özengin, Cemil Yılmaz, Berna Kırıl Mert
Format: Article
Language:English
Published: Sakarya University 2022-12-01
Series:Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi
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Online Access:https://dergipark.org.tr/tr/download/article-file/2201538
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author Nihan Özengin
Cemil Yılmaz
Berna Kırıl Mert
author_facet Nihan Özengin
Cemil Yılmaz
Berna Kırıl Mert
author_sort Nihan Özengin
collection DOAJ
description Active substances of drugs can cause various adverse effects by accumulating in the ecosystem. Many medications are resistant to biodegradation, given the recipient media in conventional wastewater treatment plants, and are thus released into the environment after only partial purification or no purification at all. The study focuses on 13 different pharmaceutical compounds belonging to drug classes of anti-depressants, antiepileptic’s, anti-inflammatories, beta-blockers, lidocaine, and stimulants. These compounds were selected with reference to the literature as the ones most commonly encountered in domestic wastewater, surface, and groundwater. The presence of these compounds in the wastewater samples from Sakarya sewage and wastewater treatment plant was investigated. For this purpose, composite samples were taken at various sampling points, and duly analyzed. The analysis revealed the presence of the pharmaceutical residues in the sewage waters from Sakarya Municipality. Some of them were still present in the effluent of the treatment plant. On the other hand, fluoxetine, propranolol, and metoprolol drug active ingredients were not detected at any sampling point. Among all the compounds examined, the highest percentage of residues were observed in the case of active caffeine and paracetamol. In the light of these findings, advanced treatment units such as high-pressure membrane systems (including ozonizing, ultrafiltration, and reverse osmosis) can help adsorption rates at the treatment plant, increasing removal efficiency regarding drug compounds.
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series Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi
spelling doaj-art-b8ecfecf57d846eab175d6bd3f3d359a2025-08-20T01:57:40ZengSakarya UniversitySakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi2147-835X2022-12-012661209122310.16984/saufenbilder.106021228Investigation of Pharmaceuticals in Sakarya Sewage WastewaterNihan Özengin0https://orcid.org/0000-0002-7647-921XCemil Yılmazhttps://orcid.org/0000-0002-0283-6296Berna Kırıl Mert1https://orcid.org/0000-0001-6993-7916Uludağ ÜniversitesiSAKARYA ÜNİVERSİTESİActive substances of drugs can cause various adverse effects by accumulating in the ecosystem. Many medications are resistant to biodegradation, given the recipient media in conventional wastewater treatment plants, and are thus released into the environment after only partial purification or no purification at all. The study focuses on 13 different pharmaceutical compounds belonging to drug classes of anti-depressants, antiepileptic’s, anti-inflammatories, beta-blockers, lidocaine, and stimulants. These compounds were selected with reference to the literature as the ones most commonly encountered in domestic wastewater, surface, and groundwater. The presence of these compounds in the wastewater samples from Sakarya sewage and wastewater treatment plant was investigated. For this purpose, composite samples were taken at various sampling points, and duly analyzed. The analysis revealed the presence of the pharmaceutical residues in the sewage waters from Sakarya Municipality. Some of them were still present in the effluent of the treatment plant. On the other hand, fluoxetine, propranolol, and metoprolol drug active ingredients were not detected at any sampling point. Among all the compounds examined, the highest percentage of residues were observed in the case of active caffeine and paracetamol. In the light of these findings, advanced treatment units such as high-pressure membrane systems (including ozonizing, ultrafiltration, and reverse osmosis) can help adsorption rates at the treatment plant, increasing removal efficiency regarding drug compounds.https://dergipark.org.tr/tr/download/article-file/2201538pharmacceuticals compoundssewage wastewatertreatmentremoval
spellingShingle Nihan Özengin
Cemil Yılmaz
Berna Kırıl Mert
Investigation of Pharmaceuticals in Sakarya Sewage Wastewater
Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi
pharmacceuticals compounds
sewage wastewater
treatment
removal
title Investigation of Pharmaceuticals in Sakarya Sewage Wastewater
title_full Investigation of Pharmaceuticals in Sakarya Sewage Wastewater
title_fullStr Investigation of Pharmaceuticals in Sakarya Sewage Wastewater
title_full_unstemmed Investigation of Pharmaceuticals in Sakarya Sewage Wastewater
title_short Investigation of Pharmaceuticals in Sakarya Sewage Wastewater
title_sort investigation of pharmaceuticals in sakarya sewage wastewater
topic pharmacceuticals compounds
sewage wastewater
treatment
removal
url https://dergipark.org.tr/tr/download/article-file/2201538
work_keys_str_mv AT nihanozengin investigationofpharmaceuticalsinsakaryasewagewastewater
AT cemilyılmaz investigationofpharmaceuticalsinsakaryasewagewastewater
AT bernakırılmert investigationofpharmaceuticalsinsakaryasewagewastewater