Sulfonamide Residues: Honey Quality in the Czech Market
In this study, we determined four sulfonamide compounds (sulfadiazine, sulfadoxine, sulfamethoxazole, and sulfathiazole) in honey marketed in the Czech Republic (Brno). The content of these compounds was monitored in 50 honeys with different botanical and geographical origin. Preanalytical treatment...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Food Quality |
| Online Access: | http://dx.doi.org/10.1155/2018/2939207 |
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| _version_ | 1832561312920502272 |
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| author | Sandra Dluhošová Ivana Borkovcová Lenka Kaniová Lenka Vorlová |
| author_facet | Sandra Dluhošová Ivana Borkovcová Lenka Kaniová Lenka Vorlová |
| author_sort | Sandra Dluhošová |
| collection | DOAJ |
| description | In this study, we determined four sulfonamide compounds (sulfadiazine, sulfadoxine, sulfamethoxazole, and sulfathiazole) in honey marketed in the Czech Republic (Brno). The content of these compounds was monitored in 50 honeys with different botanical and geographical origin. Preanalytical treatment included acidic hydrolysis with 10% trichloroacetic acid (TCA) and double extraction with acetonitrile and dichloromethane. Chromatographic analysis was performed by ultraperformance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS) using a triple quadrupole (QqQ) in positive ionization mode (ESI+). For separation, the mobile phase was a 0.05% aqueous solution of formic acid (A) and 0.05% formic acid in methanol (B) with a gradient elution of 0–3 minutes: 10% B; 3–3.6 min: 90% B; and 3.6–5 min: 10% B, flow rate 0.30 ml/min. Three positive samples (6%) were found containing sulfadiazine (232.88 and 618.87 μg/kg) and sulfamethoxazole (62.64 μg/kg). According to the country of origin, two of these honeys were from European Union (EU) countries, and one was labeled as a blend of honey from EU and non-EU countries. |
| format | Article |
| id | doaj-art-b8dba4ab636546788899b2b3c848501f |
| institution | Kabale University |
| issn | 0146-9428 1745-4557 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Food Quality |
| spelling | doaj-art-b8dba4ab636546788899b2b3c848501f2025-02-03T01:25:20ZengWileyJournal of Food Quality0146-94281745-45572018-01-01201810.1155/2018/29392072939207Sulfonamide Residues: Honey Quality in the Czech MarketSandra Dluhošová0Ivana Borkovcová1Lenka Kaniová2Lenka Vorlová3Department of Milk Hygiene and Technology, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Palackého Tř. 1946/1, 612 42 Brno, Czech RepublicDepartment of Milk Hygiene and Technology, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Palackého Tř. 1946/1, 612 42 Brno, Czech RepublicDepartment of Milk Hygiene and Technology, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Palackého Tř. 1946/1, 612 42 Brno, Czech RepublicDepartment of Milk Hygiene and Technology, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Palackého Tř. 1946/1, 612 42 Brno, Czech RepublicIn this study, we determined four sulfonamide compounds (sulfadiazine, sulfadoxine, sulfamethoxazole, and sulfathiazole) in honey marketed in the Czech Republic (Brno). The content of these compounds was monitored in 50 honeys with different botanical and geographical origin. Preanalytical treatment included acidic hydrolysis with 10% trichloroacetic acid (TCA) and double extraction with acetonitrile and dichloromethane. Chromatographic analysis was performed by ultraperformance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS) using a triple quadrupole (QqQ) in positive ionization mode (ESI+). For separation, the mobile phase was a 0.05% aqueous solution of formic acid (A) and 0.05% formic acid in methanol (B) with a gradient elution of 0–3 minutes: 10% B; 3–3.6 min: 90% B; and 3.6–5 min: 10% B, flow rate 0.30 ml/min. Three positive samples (6%) were found containing sulfadiazine (232.88 and 618.87 μg/kg) and sulfamethoxazole (62.64 μg/kg). According to the country of origin, two of these honeys were from European Union (EU) countries, and one was labeled as a blend of honey from EU and non-EU countries.http://dx.doi.org/10.1155/2018/2939207 |
| spellingShingle | Sandra Dluhošová Ivana Borkovcová Lenka Kaniová Lenka Vorlová Sulfonamide Residues: Honey Quality in the Czech Market Journal of Food Quality |
| title | Sulfonamide Residues: Honey Quality in the Czech Market |
| title_full | Sulfonamide Residues: Honey Quality in the Czech Market |
| title_fullStr | Sulfonamide Residues: Honey Quality in the Czech Market |
| title_full_unstemmed | Sulfonamide Residues: Honey Quality in the Czech Market |
| title_short | Sulfonamide Residues: Honey Quality in the Czech Market |
| title_sort | sulfonamide residues honey quality in the czech market |
| url | http://dx.doi.org/10.1155/2018/2939207 |
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