A simple prediction score system for malignant brain edema progression in large hemispheric infarction.
Malignant brain edema (MBE) due to hemispheric infarction can result in brain herniation, poor outcomes, and death; outcome may be improved if certain interventions, such as decompressive craniectomy, are performed early. We sought to generate a prediction score to easily identify those patients at...
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Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171425&type=printable |
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| author | KwangWook Jo Suhas S Bajgur Hoon Kim Huimahn A Choi Pil-Woo Huh Kiwon Lee |
| author_facet | KwangWook Jo Suhas S Bajgur Hoon Kim Huimahn A Choi Pil-Woo Huh Kiwon Lee |
| author_sort | KwangWook Jo |
| collection | DOAJ |
| description | Malignant brain edema (MBE) due to hemispheric infarction can result in brain herniation, poor outcomes, and death; outcome may be improved if certain interventions, such as decompressive craniectomy, are performed early. We sought to generate a prediction score to easily identify those patients at high risk for MBE. 121 patients with large hemispheric infarction (LHI) (2011 to 2014) were included. Patients were divided into two groups: those who developed MBE and those who did not. Independent predictors of MBE were identified by logistic regression and a score was developed. Four factors were independently associated with MBE: baseline National Institutes of Health Stroke Scale (NIHSS) score (p = 0.048), Alberta Stroke Program Early Computed Tomography Score (ASPECTS) (p = 0.007), collateral score (CS) (p<0.001) and revascularization failure (p = 0.013). Points were assigned for each factor as follows: NIHSS ≤ 8 (= 0), 9-17 (= 1), ≥ 18 (= 2); ASPECTS≤ 7 (= 1), >8 (= 0); CS<2 (= 1), ≥2 (= 0); revascularization failure (= 1),success (= 0). The MBE Score (MBES) represents the sum of these individual points. Of 26 patients with a MBES of 0 to 1, none developed MBE. All patients with a MBES of 6 developed MBE. Both MBE development and functional outcomes were strongly associated with the MBES (p = 0.007 and 0.002, respectively). The MBE score is a simple reliable tool for the prediction of MBE. |
| format | Article |
| id | doaj-art-b8cf8db2564a444094f423f23cfdfcee |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-b8cf8db2564a444094f423f23cfdfcee2025-08-20T02:03:58ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01122e017142510.1371/journal.pone.0171425A simple prediction score system for malignant brain edema progression in large hemispheric infarction.KwangWook JoSuhas S BajgurHoon KimHuimahn A ChoiPil-Woo HuhKiwon LeeMalignant brain edema (MBE) due to hemispheric infarction can result in brain herniation, poor outcomes, and death; outcome may be improved if certain interventions, such as decompressive craniectomy, are performed early. We sought to generate a prediction score to easily identify those patients at high risk for MBE. 121 patients with large hemispheric infarction (LHI) (2011 to 2014) were included. Patients were divided into two groups: those who developed MBE and those who did not. Independent predictors of MBE were identified by logistic regression and a score was developed. Four factors were independently associated with MBE: baseline National Institutes of Health Stroke Scale (NIHSS) score (p = 0.048), Alberta Stroke Program Early Computed Tomography Score (ASPECTS) (p = 0.007), collateral score (CS) (p<0.001) and revascularization failure (p = 0.013). Points were assigned for each factor as follows: NIHSS ≤ 8 (= 0), 9-17 (= 1), ≥ 18 (= 2); ASPECTS≤ 7 (= 1), >8 (= 0); CS<2 (= 1), ≥2 (= 0); revascularization failure (= 1),success (= 0). The MBE Score (MBES) represents the sum of these individual points. Of 26 patients with a MBES of 0 to 1, none developed MBE. All patients with a MBES of 6 developed MBE. Both MBE development and functional outcomes were strongly associated with the MBES (p = 0.007 and 0.002, respectively). The MBE score is a simple reliable tool for the prediction of MBE.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171425&type=printable |
| spellingShingle | KwangWook Jo Suhas S Bajgur Hoon Kim Huimahn A Choi Pil-Woo Huh Kiwon Lee A simple prediction score system for malignant brain edema progression in large hemispheric infarction. PLoS ONE |
| title | A simple prediction score system for malignant brain edema progression in large hemispheric infarction. |
| title_full | A simple prediction score system for malignant brain edema progression in large hemispheric infarction. |
| title_fullStr | A simple prediction score system for malignant brain edema progression in large hemispheric infarction. |
| title_full_unstemmed | A simple prediction score system for malignant brain edema progression in large hemispheric infarction. |
| title_short | A simple prediction score system for malignant brain edema progression in large hemispheric infarction. |
| title_sort | simple prediction score system for malignant brain edema progression in large hemispheric infarction |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171425&type=printable |
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