In Silico and In Vitro development of novel small interfering RNAs (siRNAs) to inhibit SARS-CoV-2

In Silico and In Vitro development of novel small interfering RNAs (siRNAs) to inhibit SARS-CoV-2

SARS-CoV-2 is causing severe to moderate respiratory tract infections, posing global health, social life, and economic threats. Our design strategy for siRNAs differs from existing studies through a step-by-step filtration process utilizing integrative bioinformatics protocols and web tools. Stage o...

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Bibliographic Details
Main Authors: Noha Samir Taibe, Sara H. Mahmoud, Maimona A. Kord, Mohamed Ahmed Badawy, Mahmoud Shehata, Mahmoud Elhefnawi
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
SARS-CoV-2
Therapy
Silencing
SiRNA
Non-structure proteins (NSP)
Open reading frame(ORF)
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037025001035
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