Reduced expression of IFIH1 is protective for type 1 diabetes.

Reduced expression of IFIH1 is protective for type 1 diabetes.

IFIH1 (interferon induced with helicase C domain 1), also known as MDA5 (melanoma differentiation-associated protein 5), is one of a family of intracellular proteins known to recognise viral RNA and mediate the innate immune response. IFIH1 is causal in type 1 diabetes based on the protective associ...

Full description

Saved in:
Bibliographic Details
Main Authors: Kate Downes, Marcin Pekalski, Karen L Angus, Matthew Hardy, Sarah Nutland, Deborah J Smyth, Neil M Walker, Chris Wallace, John A Todd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0012646&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items