Genomic epidemiology of Plasmodium knowlesi reveals putative genetic drivers of adaptation in Malaysia.

Genomic epidemiology of Plasmodium knowlesi reveals putative genetic drivers of adaptation in Malaysia.

Sabah, Malaysia, has amongst the highest burden of human Plasmodium knowlesi infection in the world, associated with increasing encroachment on the parasite's macaque host habitat. However, the genomic make-up of P. knowlesi in Sabah was previously poorly understood. To inform on local patterns...

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Main Authors: Jacob A F Westaway, Ernest Diez Benavente, Sarah Auburn, Michal Kucharski, Nicolas Aranciaga, Sourav Nayak, Timothy William, Giri S Rajahram, Kim A Piera, Kamil Braima, Angelica F Tan, Danshy A Alaza, Bridget E Barber, Chris Drakeley, Roberto Amato, Edwin Sutanto, Hidayat Trimarsanto, Jenarun Jelip, Nicholas M Anstey, Zbynek Bozdech, Matthew Field, Matthew J Grigg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0012885
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